| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2167991 | B | Inhibition of TACE using Mca-PLAQAV-Dpa-RSSSR-NH2 as substrate preincubated 15 mins measured every 30 sec for 30 mins | 7 | single protein format | Scientific Literature | |||
| 2. | ALA2167992 | B | Inhibition of human ADAMTS-5 expressed in CHO cells using WAAG-3R as substrate preincubated for 15 mins measured after 1 hr by FRET assay | Homo sapiens | 54 | cell-based format | Scientific Literature | ||
| 3. | ALA2167993 | B | Inhibition of ADAMTS-4 using WAAG-3R as substrate preincubated for 15 mins measured after 1 hr | 7 | single protein format | Scientific Literature | |||
| 4. | ALA2167994 | B | Inhibition of MMP-13 using 5-FAM-TPGPLGL[Dap- (DNP)]ARRK(5-TAMRA)-amide as substrate after 45 mins | 7 | single protein format | Scientific Literature | |||
| 5. | ALA2167995 | B | Inhibition of ADAMTS-1 using FAM (5-carbosyfluorescein)-AE*LQGRPISIAK substrate after 2 hrs | 7 | single protein format | Scientific Literature | |||
| 6. | ALA2168189 | B | Competitive inhibition of human ADAMTS-5 expressed in CHO cells using WAAG-3R as substrate | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA2168190 | T | Toxicity in human osteoarthritis cartilage explants at 2 to 10 uM by Alamar Blue assay | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 8. | ALA2168191 | B | Selectivity ratio of IC50 for human ADAMTS-5 over IC50 for ADAMTS-1 | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 9. | ALA2168192 | B | Selectivity ratio of IC50 for human ADAMTS-5 over IC50 for MMP-13 | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 10. | ALA2168193 | B | Selectivity ratio of IC50 for human ADAMTS-5 over IC50 for TACE | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 11. | ALA2168194 | B | Selectivity ratio of IC50 for human ADAMTS-5 over IC50 for ADAMTS-4 | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 12. | ALA2168195 | B | Inhibition of human ADAMTS-5 expressed in CHO cells using WAAG-3R as substrate in presence of 1 to 100 microM of zinc | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA2168197 | F | Inhibition of IL-1beta/ oncostatin-M-stimulated cartilage degradation in human osteoarthritis cartilage explants assessed as the inhibition of glycosaminoglycan release at 2 to 10 uM after 2 hrs by DMMB dye staining | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 14. | ALA2168199 | F | Inhibition of IL-1beta/ oncostatin-M-stimulated cartilage degradation in human osteoarthritis cartilage explants assessed as the inhibition of aggrecanase specific 374ARGS neoepitope release after 2 hrs by sandwich ELISA | Homo sapiens | 2 | tissue-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!