# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA771603 | F | In vitro inhibition of potassium-contracted rabbit aorta strips | Oryctolagus cuniculus | 31 | ALA1125542 | organism-based format | Scientific Literature | |
2. | ALA815532 | F | In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) in potassium-depolarized rabbit thoracic aorta at 1 uM | Oryctolagus cuniculus | 2 | ALA1125053 | tissue-based format | Scientific Literature | |
3. | ALA842889 | F | In vivo evaluation for the antihypertensive effect in the spontaneously hypertensive rat is % decrease in blood pressure during post drug administration at 135 umol/kg peroral; 6/8 | Rattus norvegicus | 1 | ALA1125542 | organism-based format | Scientific Literature | |
4. | ALA4192100 | B | Modulation of [3H]NCS-382 binding to alpha4betadelta GABAA receptor in rat cortical membranes after 1 hr by TopCount scintillation counting method | Rattus norvegicus | 42 | ALA4190247 | cell membrane format | Scientific Literature | |
5. | ALA4192101 | B | Modulation of [3H]NCS-382 binding to alpha4betadelta GABAA receptor in rat cortical membranes assessed as [3H]NCS-382 binding at 100 uM after 1 hr by TopCount scintillation counting method relative to control | Rattus norvegicus | 40 | ALA4190247 | cell membrane format | Scientific Literature | |
6. | ALA4414681 | F | Vasodilating activity in Wistar rat aortic rings assessed as reduction in phenylephrine-induced contractions | Rattus norvegicus | 9 | ALA4414544 | tissue-based format | Scientific Literature | |
7. | ALA4414682 | F | Vasodilating activity in Wistar rat aortic rings assessed as reduction in phenylephrine-induced contractions relative to control | Rattus norvegicus | 9 | ALA4414544 | tissue-based format | Scientific Literature | |
8. | ALA4414683 | F | Vasodilating activity in Wistar rat aortic rings assessed as reduction in KCl-induced contractions | Rattus norvegicus | 9 | ALA4414544 | tissue-based format | Scientific Literature | |
9. | ALA4414684 | F | Vasodilating activity in Wistar rat aortic rings assessed as reduction in KCl-induced contractions relative to control | Rattus norvegicus | 9 | ALA4414544 | tissue-based format | Scientific Literature | |
10. | ALA4414685 | F | Vasodilating activity in Wistar rat aortic rings assessed as reduction in phenylephrine-induced contractions in presence of Cacl2 in calcium free Krebs medium incubated for 1 hr relative to control | Rattus norvegicus | 3 | ALA4414544 | tissue-based format | Scientific Literature | |
11. | ALA4414686 | F | Antiproliferative activity against human MM1S cells incubated for 72 hrs by MTT assay | Homo sapiens | 9 | ALA4414544 | cell-based format | Scientific Literature | |
12. | ALA4414687 | F | Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay | Homo sapiens | 9 | ALA4414544 | cell-based format | Scientific Literature | |
13. | ALA4414688 | F | Antiproliferative activity against human HCT116 cells incubated for 72 hrs by MTT assay | Homo sapiens | 9 | ALA4414544 | cell-based format | Scientific Literature | |
14. | ALA4414689 | F | Antiproliferative activity against human MCF7 cells incubated for 72 hrs by MTT assay | Homo sapiens | 9 | ALA4414544 | cell-based format | Scientific Literature | |
15. | ALA4414690 | A | Cytotoxicity against human MSC assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 9 | ALA4414544 | assay format | Scientific Literature | |
16. | ALA4414691 | B | Inhibition of Eg5 in human MCF7 cells assessed as increase in monopolar spindle formation at 100 uM incubated for 24 hrs by DAPI staining based confocal microscopic method | Homo sapiens | 3 | ALA4414544 | cell-based format | Scientific Literature | |
17. | ALA4414692 | B | Inhibition of L-type calcium channel in Wistar rat aortic rings assessed as reduction in (-)-Bay K8644-induced contractions at 10'-4 M measured after 20 mins | Rattus norvegicus | 3 | ALA4414544 | protein format | Scientific Literature | |
18. | ALA4414693 | B | Inhibition of L-type calcium channel in Wistar rat aortic rings assessed as reduction in (-)-Bay K8644-induced contractions at 10'-5 M measured after 20 mins | Rattus norvegicus | 1 | ALA4414544 | protein format | Scientific Literature |