# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2169623 | B | Binding affinity to Mycobacterium smegmatis mc2 155 EthR assessed as protein thermal unfolding at 20 uM by SYPRO Orange dye based thermal shift assay | Mycolicibacterium smegmatis MC2 155 | 43 | single protein format | Scientific Literature | ||
2. | ALA2169624 | B | Inhibition of EthR in Mycobacterium tuberculosis H37Rv-GFP infected in mouse Raw 264.7 cells assessed as boosting of 0.1 uM ethionamide-induced microbial growth inhibition at 10 uM by automated fluorescent confocal microscopy | Mycobacterium tuberculosis H37Rv | 24 | cell-based format | Scientific Literature | ||
3. | ALA2169625 | B | Inhibition of EthR in Mycobacterium tuberculosis H37Rv-GFP infected in mouse Raw 264.7 cells assessed as compound concentration allowing 0.1 uM ethionamide to inhibit 50% microbial growth by automated fluorescent confocal microscopy | Mycobacterium tuberculosis H37Rv | 6 | cell-based format | Scientific Literature | ||
4. | ALA2166083 | F | Antituberculosis activity against Mycobacterium tuberculosis H37Rv-GFP infected in mouse Raw 264.7 cells assessed as microbial growth inhibition at 10 uM by automated fluorescent confocal microscopy | Mycobacterium tuberculosis | 1 | organism-based format | Scientific Literature |