| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2168708 | B | Inhibition of human recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage incubated for 1 hrs by QFRET assay | Homo sapiens | 38 | single protein format | Scientific Literature | ||
| 2. | ALA2168709 | B | Inhibition of human recombinant CatL assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage by QFRET assay | Homo sapiens | 33 | single protein format | Scientific Literature | ||
| 3. | ALA2168710 | B | Inhibition of human recombinant CatS assessed as suppression of enzyme-mediated Z-Val-Val-Arg-AMC cleavage by QFRET assay | Homo sapiens | 36 | single protein format | Scientific Literature | ||
| 4. | ALA2168711 | B | Inhibition of human recombinant CatB assessed as suppression of enzyme-mediated Z-Arg-Arg-AMC cleavage by QFRET assay | Homo sapiens | 34 | single protein format | Scientific Literature | ||
| 5. | ALA2168713 | P | Lipophilicity, log D of the compound at pH 7.4 | 32 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA2168714 | A | Intrinsic clearance in dog hepatocytes assessed as metabolic turnover measured per 10'6 cells | Canis lupus familiaris | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA2168715 | A | Plasma clearance in Alderley Park Han Wistar rat at 2.0 mg/kg, po and 2.0 mg/kg, iv administered as single dose | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 8. | ALA2168716 | A | Plasma clearance in Beagle dog at 1.0 mg/kg, po and 1.0 mg/kg, iv administered as single dose | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA2168717 | A | Volume of distribution at steady state in Alderley Park Han Wistar rat at 2.0 mg/kg, po and 2.0 mg/kg, iv administered as single dose | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA2168917 | A | Volume of distribution at steady state in Beagle dog at 1.0 mg/kg, po and 1.0 mg/kg, iv administered as single dose | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA2168918 | A | Half life in Alderley Park Han Wistar rat at 2.0 mg/kg, iv administered as single dose | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 12. | ALA2168919 | A | Half life in Beagle dog at 1.0 mg/kg, iv administered as single dose | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA2168920 | A | Oral bioavailability in Alderley Park Han Wistar rat at 2.0 mg/kg administered as single dose | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 14. | ALA2168921 | A | Oral bioavailability in Beagle dog at 2.0 mg/kg administered as single dose | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 15. | ALA2168924 | A | Fraction unbound in human serum | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
| 16. | ALA2168925 | A | Intrinsic clearance in human hepatocytes assessed as metabolic turnover measured per 10'6 cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA2168927 | A | Intrinsic clearance in human liver microsomes assessed as metabolic turnover | Homo sapiens | 31 | microsome format | Scientific Literature | ||
| 18. | ALA2168928 | A | Fraction unbound in dog serum | Canis lupus familiaris | 3 | cell-free format | Scientific Literature | ||
| 19. | ALA2168929 | P | Aqueous solubility of the compound at pH 7.4 | 32 | small-molecule physicochemical format | Scientific Literature | |||
| 20. | ALA2168930 | A | Fraction unbound in rat serum | Rattus norvegicus | 3 | cell-free format | Scientific Literature |
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