# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2165976 | F | Cell cycle arrest in human Jurkat E6-1 cells assessed as accumulation at G0/G1 phase at 2.2 uM after 24 hrs by FACS flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA2166250 | F | Cell cycle arrest in human Jurkat E6-1 cells assessed as accumulation at S phase at 2.2 uM after 24 hrs by FACS flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA2167655 | F | Cell cycle arrest in human Jurkat E6-1 cells assessed as accumulation at G2/M phase at 2.2 uM after 24 hrs by FACS flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA2167663 | F | Induction of DNA damage response in human M21 cells assessed as phosphorylation of H2AX into gammaH2AX at IC50 after 24 hrs by DAPI staining-based immunofluorescence assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
5. | ALA2167666 | F | Antitumor activity against human HT1080 cells xenografted in chicken chorioallantoic membrane assessed as inhibition of tumor growth at 30 ug per egg, iv administered on day 11 measured on day 17 by CAM assay | Homo sapiens | 7 | organism-based format | Scientific Literature | ||
6. | ALA2167669 | T | Toxicity in fertilized chicken embryo assessed as mortality rate at 30 ug per egg, iv administered on day 11 measured on day 17 by CAM assay | Gallus gallus | 5 | organism-based format | Scientific Literature | ||
7. | ALA2169469 | F | Cytotoxicity against human HT-29 cells after 48 hrs by SRB assay | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
8. | ALA2169470 | F | Cytotoxicity against human M21 cells after 48 hrs by SRB assay | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
9. | ALA2169471 | F | Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
10. | ALA3635234 | F | Antiproliferative activity against human HT1080 cells assessed as growth inhibition incubated for 48 hrs by sulforhodamine B assay | Homo sapiens | 55 | cell-based format | Scientific Literature | ||
11. | ALA3635235 | F | Antiproliferative activity against human M21 cells assessed as growth inhibition incubated for 48 hrs by sulforhodamine B assay | Homo sapiens | 55 | cell-based format | Scientific Literature | ||
12. | ALA3635236 | F | Antiproliferative activity against human HT-29 cells assessed as growth inhibition incubated for 48 hrs by sulforhodamine B assay | Homo sapiens | 55 | cell-based format | Scientific Literature | ||
13. | ALA3635237 | F | Antiproliferative activity against human MCF7 cells assessed as growth inhibition incubated for 48 hrs by sulforhodamine B assay | Homo sapiens | 55 | cell-based format | Scientific Literature | ||
14. | ALA4272237 | F | Alkylating activity at DNA (unknown origin) after 90 mins by colorimetric NBP assay | Not specified | 18 | assay format | Scientific Literature | ||
15. | ALA4272238 | F | Alkylating activity at DNA (unknown origin) after 90 mins by colorimetric NBP assay relative to chlorambucil | Not specified | 17 | assay format | Scientific Literature | ||
16. | ALA4723392 | F | Antiproliferative activity against human HT-29 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
17. | ALA4723393 | F | Antiproliferative activity against human M21 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
18. | ALA4723394 | B | Inhibition of recombinant N-terminal His-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli using L-DHO as substrate measured every 10 mins for 90 mins in presence of decylubiquinone by DCIP based colorimetric assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
19. | ALA4723395 | F | Antiproliferative activity against human HT-29 cells assessed as cell growth inhibition measured after 48 hrs in presence of uridine by SRB assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
20. | ALA4723396 | F | Antiproliferative activity against human M21 cells assessed as cell growth inhibition measured after 48 hrs in presence of uridine by SRB assay | Homo sapiens | 3 | cell-based format | Scientific Literature |