# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2173649 | F | Antimetastatic activity against mouse B16F10 cells xenografted in C57BL mouse assessed as decrease in lung metastasis at 25 mg/kg, ip administered QD measured after 21 days | Mus musculus | 2 | organism-based format | Scientific Literature | ||
2. | ALA2173726 | F | Antimetastatic activity against mouse B16F10 cells xenografted in C57BL mouse assessed as decrease in lung metastasis at 12.5 mg/kg, ip administered QD measured after 21 days | Mus musculus | 2 | organism-based format | Scientific Literature | ||
3. | ALA2173727 | F | Antimetastatic activity against mouse B16F10 cells xenografted in C57BL mouse assessed as decrease in lung metastasis at 50 mg/kg, po administered QD measured after 21 days | Mus musculus | 3 | organism-based format | Scientific Literature | ||
4. | ALA2173728 | F | Antimetastatic activity against mouse B16F10 cells xenografted in C57BL mouse assessed as decrease in lung metastasis at 50 mg/kg, ip administered QD measured after 21 days | Mus musculus | 2 | organism-based format | Scientific Literature | ||
5. | ALA2173729 | B | Inhibition of human Carbonic anhydrase 9-mediated CO2 hydration by stopped-flow method | Homo sapiens | 21 | single protein format | Scientific Literature | ||
6. | ALA2173730 | B | Inhibition of human Carbonic anhydrase 12-mediated CO2 hydration by stopped-flow method | Homo sapiens | 21 | single protein format | Scientific Literature | ||
7. | ALA2173731 | B | Inhibition of human Carbonic anhydrase 2-mediated CO2 hydration by stopped-flow method | Homo sapiens | 21 | single protein format | Scientific Literature | ||
8. | ALA2173732 | B | Inhibition of human Carbonic anhydrase 1-mediated CO2 hydration by stopped-flow method | Homo sapiens | 21 | single protein format | Scientific Literature | ||
9. | ALA2173733 | B | Inhibition of human recombinant MMP2 measured every 5 mins for 3 hrs | Homo sapiens | 5 | single protein format | Scientific Literature | ||
10. | ALA2175866 | B | Binding affinity to bone mineral hydroxyapatite at 100 uM after 17 hrs | 1 | assay format | Scientific Literature | |||
11. | ALA2175867 | A | Half life in Sprague-Dawley rat at 33 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
12. | ALA2175868 | A | Volume of distribution at steady state in Sprague-Dawley rat at 33 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
13. | ALA2175869 | A | Cytotoxicity against human HeLa cells assessed as increase in LDH level up to 100 uM after 24 hrs in normoxic condition by spectrophotometric analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA2175870 | A | Cytotoxicity against human HT1080 cells assessed as increase in LDH level up to 100 uM after 24 hrs in normoxic condition by spectrophotometric analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA2175871 | F | Cytotoxicity against human HT1080 cells assessed as increase in LDH level after 24 hrs in hypoxic condition by spectrophotometric analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA2175872 | F | Cytotoxicity against human HeLa cells assessed as increase in LDH level after 24 hrs in hypoxic condition by spectrophotometric analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA2175873 | F | Cytotoxicity against human HT1080 cells assessed as increase in LDH level at 1 uM after 24 hrs in hypoxic condition by spectrophotometric analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA2175874 | F | Cytotoxicity against human HT1080 cells assessed as increase in LDH level at 10 uM after 24 hrs in hypoxic condition by spectrophotometric analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA2175875 | F | Cytotoxicity against human HeLa cells assessed as increase in LDH level at 50 uM after 24 hrs in hypoxic condition by spectrophotometric analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA2175876 | F | Cytotoxicity against human HT1080 cells assessed as increase in LDH level at 50 uM after 24 hrs in hypoxic condition by spectrophotometric analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature |