# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2174546 | A | Cytotoxicity in human polymorphonuclear leukocytes assessed as cell viability at 10 uM after 24 hrs by MTT assay | Homo sapiens | 14 | ALA2169781 | cell-based format | Scientific Literature | |
2. | ALA2174547 | B | Inhibition of 5-lipoxygenase-mediated 5(S)-H(p)ETE formation in fMLP-stimulated human PMNL incubated 10 mins prior to fMLP challenge | Homo sapiens | 36 | ALA2169781 | single protein format | Scientific Literature | |
3. | ALA2172850 | B | Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 after 15 mins by RP-HPLC analysis | Homo sapiens | 36 | ALA2169781 | microsome format | Scientific Literature | |
4. | ALA2173194 | B | Inhibition of human recombinant 5-lipoxygenase-mediated product formation from arachidonic acid after 5 to 10 mins by HPLC analysis | Homo sapiens | 35 | ALA2169781 | single protein format | Scientific Literature | |
5. | ALA2173195 | B | Inhibition of human recombinant 5-lipoxygenase-mediated product formation from arachidonic acid assessed as remaining activity at 10 uM after 5 to 10 mins by HPLC analysis | Homo sapiens | 14 | ALA2169781 | single protein format | Scientific Literature | |
6. | ALA2173197 | B | Inhibition of ovine COX-1 mediated formation of 12-HHT from arachidonic acid assessed as remaining activity at 10 uM after 5 mins by HPLC analysis | Ovis aries | 15 | ALA2169781 | single protein format | Scientific Literature | |
7. | ALA2173198 | B | Inhibition of human recombinant COX-2 mediated formation of 12-HHT from arachidonic acid assessed as remaining activity at 10 uM after 5 mins by HPLC analysis | Homo sapiens | 15 | ALA2169781 | single protein format | Scientific Literature |