# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2173314 | B | Inhibition of NHE1 in rat platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 mins | Rattus norvegicus | 1 | ALA2169836 | cell-free format | Scientific Literature | |
2. | ALA2173315 | F | Inhibition of ischemia reperfusion injury-induced decrease in left ventricular developed pressure in Langendorff isolated perfused Sprague-Dawley rat heart at 10 nM after 30 mins | Rattus norvegicus | 1 | ALA2169836 | tissue-based format | Scientific Literature | |
3. | ALA2173317 | F | Inhibition of ischemia reperfusion injury-induced decrease in left ventricular developed pressure in Langendorff isolated perfused Sprague-Dawley rat heart at 100 nM after 30 mins | Rattus norvegicus | 1 | ALA2169836 | tissue-based format | Scientific Literature | |
4. | ALA2173318 | A | Induction of phopspholipidosis in human U937 cells up to 50 uM after 24 hrs by Nile red flow cytometry assay | Homo sapiens | 1 | ALA2169836 | cell-based format | Scientific Literature | |
5. | ALA2173319 | A | Cytotoxicity against human HeLa cells up to 100 uM after 24 hrs | Homo sapiens | 1 | ALA2169836 | cell-based format | Scientific Literature | |
6. | ALA2173320 | T | Genotoxicity in Escherichia coli WP2 expressing uvrA up to 5000 ug/plate by Ames test in presence of S9 fraction | Escherichia coli | 1 | ALA2169836 | organism-based format | Scientific Literature | |
7. | ALA2173321 | T | Genotoxicity in Escherichia coli WP2 expressing uvrA up to 5000 ug/plate by Ames test in absence of S9 fraction | Escherichia coli | 1 | ALA2169836 | organism-based format | Scientific Literature | |
8. | ALA2173322 | T | Genotoxicity in Salmonella typhimurium TA100 up to 5000 ug/plate by Ames test in the presence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA2169836 | organism-based format | Scientific Literature | |
9. | ALA2173323 | T | Genotoxicity in Salmonella typhimurium TA100 up to 5000 ug/plate by Ames test in the absence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA2169836 | organism-based format | Scientific Literature | |
10. | ALA2173324 | T | Genotoxicity in Salmonella typhimurium TA98 up to 5000 ug/plate by Ames test in the absence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA2169836 | organism-based format | Scientific Literature | |
11. | ALA2173325 | T | Genotoxicity in Salmonella typhimurium TA98 up to 5000 ug/plate by Ames test in the presence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA2169836 | organism-based format | Scientific Literature | |
12. | ALA2173326 | T | Genotoxicity in Salmonella typhimurium TA1537 up to 5000 ug/plate by Ames test in the presence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA2169836 | organism-based format | Scientific Literature | |
13. | ALA2173327 | T | Genotoxicity in Salmonella typhimurium TA1537 up to 5000 ug/plate by Ames test in the absence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA2169836 | organism-based format | Scientific Literature | |
14. | ALA2173328 | T | Genotoxicity in Salmonella typhimurium TA1535 up to 5000 ug/plate by Ames test in the presence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA2169836 | organism-based format | Scientific Literature | |
15. | ALA2173329 | T | Genotoxicity in Salmonella typhimurium TA1535 up to 5000 ug/plate by Ames test in the absence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA2169836 | organism-based format | Scientific Literature | |
16. | ALA2173330 | A | Time dependent inhibition of CYP3A4 in human liver microsomes at up to 50 uM up to 20 mins | Homo sapiens | 1 | ALA2169836 | microsome format | Scientific Literature | |
17. | ALA2173331 | A | Oral bioavailability in overnight fasted Beagle dog at 5 mg/kg | Canis lupus familiaris | 3 | ALA2169836 | organism-based format | Scientific Literature | |
18. | ALA2173332 | A | Activation of CYP3A4 expressed in DPX cells co-transfected with human PXR at 0.1 to 10 uM | Homo sapiens | 1 | ALA2169836 | cell-based format | Scientific Literature | |
19. | ALA2173333 | A | Mean resident time in overnight fasted Beagle dog at 1 mg/kg, iv | Canis lupus familiaris | 3 | ALA2169836 | organism-based format | Scientific Literature | |
20. | ALA2173334 | A | Volume of distribution at steady state in overnight fasted Beagle dog at 1 mg/kg, iv | Canis lupus familiaris | 2 | ALA2169836 | organism-based format | Scientific Literature |