| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2173689 | B | Inhibition of marmoset placenta 17beta-HSD1 cytosolic fraction using unlabelled and [2,4,6,7-3H]estrone as substrate after 10 mins by HPLC analysis in presence of NADH | Callithrix jacchus | 2 | assay format | Scientific Literature | ||
| 2. | ALA2173690 | A | Intrinsic clearance in human liver microsomes measured per mg of protein | Homo sapiens | 4 | microsome format | Scientific Literature | ||
| 3. | ALA2173691 | A | Inhibition of human CYP1A2 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 4. | ALA2173692 | A | Inhibition of human CYP2C9 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 5. | ALA2173693 | A | Inhibition of human CYP2C19 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA2173694 | A | Inhibition of human CYP2D6 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 7. | ALA2173695 | A | Inhibition of human CYP3A4 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 8. | ALA2173696 | B | Inhibition of marmoset placenta 17beta-HSD1 cytosolic fraction using unlabelled and [2,4,6,7-3H]estrone as substrate at 50 nM after 10 mins by HPLC analysis in presence of NADH | Callithrix jacchus | 1 | assay format | Scientific Literature | ||
| 9. | ALA2173697 | B | Inhibition of marmoset placenta 17beta-HSD2 microsomal fraction using unlabelled and [2,4,6,7-3H]estradiol as substrate at 50 nM after 20 mins by HPLC analysis in presence of NAD+ | Callithrix jacchus | 4 | assay format | Scientific Literature | ||
| 10. | ALA2173699 | B | Inhibition of 17beta-HSD1 in human T47D cells using unlabelled and [2,4,6,7-3H]estrone as substrate preincubated for 30 mins prior to substrate addition measured 0.5 hrs post substrate addition | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 11. | ALA2173700 | B | Displacement of [2,4,6,7-3H]estradiol from recombinant human ERbeta after 1 hr by liquid scintillation counter relative to estradiol | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 12. | ALA2173701 | B | Displacement of [2,4,6,7-3H]estradiol from recombinant human ERalpha after 1 hr by liquid scintillation counter relative to estradiol | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 13. | ALA2173702 | B | Selectivity ratio of IC50 for human placenta 17beta-HSD2 microsomal fraction to IC50 for human placenta 17beta-HSD1 cytosolic fraction | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 14. | ALA2173705 | B | Inhibition of human placenta 17beta-HSD1 cytosolic fraction using unlabelled and [2,4,6,7-3H]estrone as substrate after 10 mins by HPLC analysis in presence of NADH | Homo sapiens | 18 | assay format | Scientific Literature | ||
| 15. | ALA2173706 | B | Inhibition of human placenta 17beta-HSD2 microsomal fraction using unlabelled and [2,4,6,7-3H]estradiol as substrate after 20 mins by HPLC analysis in presence of NAD+ | Homo sapiens | 20 | assay format | Scientific Literature | ||
| 16. | ALA2173506 | A | Inhibition of human CYP2B6 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 17. | ALA3631240 | B | Inhibition of human placental cytosolic 17beta HSD1 using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins by HPLC analysis | Homo sapiens | 49 | assay format | Scientific Literature | ||
| 18. | ALA3631243 | B | Inhibition of recombinant mouse 17beta HSD1 expressed in HEK293 cells using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate at 1 uM incubated for 10 mins by HPLC analysis | Mus musculus | 47 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!