#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2173859	Functional	Induction of apoptosis in human NCI-H146 cells xenografted in SCID mouse assessed as caspase 3 cleavage at 50 mg/kg, iv after 3 to 24 hrs by Western blot analysis	Homo sapiens	1	ALA2169845	organism-based format	Scientific Literature
2.	ALA2173860	Functional	Induction of apoptosis in human NCI-H146 cells xenografted in SCID mouse assessed as PARP cleavage at 50 mg/kg, iv after 3 to 6 hrs by Western blot analysis	Homo sapiens	1	ALA2169845	organism-based format	Scientific Literature
3.	ALA2173863	Functional	Induction of apoptosis in human NCI-H146 cells assessed as caspase 3 activation at 100 nM after 24 hrs by Western blot analysis	Homo sapiens	1	ALA2169845	cell-based format	Scientific Literature
4.	ALA2173864	Functional	Induction of apoptosis in human NCI-H146 cells assessed as PARP cleavage at 100 nM after 24 hrs by Western blot analysis	Homo sapiens	1	ALA2169845	cell-based format	Scientific Literature
5.	ALA2173867	Functional	Antitumor activity against human NCI-H146 cells xenografted in SCID mouse assessed as tumor regression at 50 mg/kg, iv administered 5 days per week for 2 weeks	Homo sapiens	1	ALA2169845	organism-based format	Scientific Literature
6.	ALA2173868	Functional	Antitumor activity against human NCI-H146 cells xenografted in SCID mouse assessed as tumor growth inhibition at 50 mg/kg, iv administered 5 days per week for 2 weeks	Homo sapiens	1	ALA2169845	organism-based format	Scientific Literature
7.	ALA2173871	Toxicity	Toxicity in SCID mouse assessed as body weight loss at 75 mg/kg, iv administered 5 days per week for 2 weeks relative to vehicle-treated control	Mus musculus	1	ALA2169845	organism-based format	Scientific Literature
8.	ALA2173947	Toxicity	Toxicity in SCID mouse assessed as body weight loss at 50 mg/kg, iv administered 5 days per week for 2 weeks relative to vehicle-treated control	Mus musculus	2	ALA2169845	organism-based format	Scientific Literature
9.	ALA2173950	Toxicity	Toxicity in iv dosed SCID mouse administered 5 days per week for 2 weeks	Mus musculus	3	ALA2169845	organism-based format	Scientific Literature
10.	ALA2173955	Functional	Induction of apoptosis in human NCI-H146 cells assessed as cell viability after 24 hrs by trypan blue exclusion assay	Homo sapiens	5	ALA2169845	cell-based format	Scientific Literature
11.	ALA2173956	Functional	Cytotoxicity against human NCI-H146 cells assessed as growth inhibition after 4 days by WST-8 assay	Homo sapiens	12	ALA2169845	cell-based format	Scientific Literature
12.	ALA2173957	Functional	Cytotoxicity against human H1417 cells assessed as growth inhibition after 4 days by WST-8 assay	Homo sapiens	12	ALA2169845	cell-based format	Scientific Literature
13.	ALA2173958	Binding	Binding affinity to N-terminal 8xHis-tagged human Mcl-1 (171 to 327 amino acid) expressed in Escherichia coli BL21 (DE3) at 5 uM after 2 hrs by fluorescence polarization assay	Homo sapiens	9	ALA2169845	assay format	Scientific Literature
14.	ALA2173959	Binding	Binding affinity to c-terminally truncated N-terminal 8xHis-tagged human Bcl-xL deletion mutant expressed in Escherichia coli BL21 (DE3) after 2 hrs by fluorescence polarization assay	Homo sapiens	30	ALA2169845	assay format	Scientific Literature
15.	ALA2173960	Binding	Inhibition of c-terminally truncated N-terminal 8xHis-tagged human Bcl-xL deletion mutant expressed in Escherichia coli BL21 (DE3) after 2 hrs by fluorescence polarization assay	Homo sapiens	29	ALA2169845	assay format	Scientific Literature
16.	ALA2173961	Binding	Binding affinity to N-terminal 6xHis-tagged human Bcl-2 expressed in Escherichia coli BL21 (DE3) after 2 hrs by fluorescence polarization assay	Homo sapiens	30	ALA2169845	assay format	Scientific Literature
17.	ALA2173962	Binding	Inhibition of N-terminal 6xHis-tagged human Bcl-2 expressed in Escherichia coli BL21 (DE3) after 2 hrs by fluorescence polarization assay	Homo sapiens	29	ALA2169845	assay format	Scientific Literature