# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2173956 | Functional | Cytotoxicity against human NCI-H146 cells assessed as growth inhibition after 4 days by WST-8 assay | Homo sapiens | 12 | ALA2169845 | cell-based format | Scientific Literature | |
2. | ALA2173957 | Functional | Cytotoxicity against human H1417 cells assessed as growth inhibition after 4 days by WST-8 assay | Homo sapiens | 12 | ALA2169845 | cell-based format | Scientific Literature | |
3. | ALA2173958 | Binding | Binding affinity to N-terminal 8xHis-tagged human Mcl-1 (171 to 327 amino acid) expressed in Escherichia coli BL21 (DE3) at 5 uM after 2 hrs by fluorescence polarization assay | Homo sapiens | 9 | ALA2169845 | assay format | Scientific Literature | |
4. | ALA2173959 | Binding | Binding affinity to c-terminally truncated N-terminal 8xHis-tagged human Bcl-xL deletion mutant expressed in Escherichia coli BL21 (DE3) after 2 hrs by fluorescence polarization assay | Homo sapiens | 30 | ALA2169845 | assay format | Scientific Literature | |
5. | ALA2173960 | Binding | Inhibition of c-terminally truncated N-terminal 8xHis-tagged human Bcl-xL deletion mutant expressed in Escherichia coli BL21 (DE3) after 2 hrs by fluorescence polarization assay | Homo sapiens | 29 | ALA2169845 | assay format | Scientific Literature | |
6. | ALA2173961 | Binding | Binding affinity to N-terminal 6xHis-tagged human Bcl-2 expressed in Escherichia coli BL21 (DE3) after 2 hrs by fluorescence polarization assay | Homo sapiens | 30 | ALA2169845 | assay format | Scientific Literature | |
7. | ALA2173962 | Binding | Inhibition of N-terminal 6xHis-tagged human Bcl-2 expressed in Escherichia coli BL21 (DE3) after 2 hrs by fluorescence polarization assay | Homo sapiens | 29 | ALA2169845 | assay format | Scientific Literature |