| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA909036 | F | Inhibition of PrP-res formation in mouse ScN2a cells relative to control | Mus musculus | 11 | cell-based format | Scientific Literature | ||
| 2. | ALA909037 | F | Inhibition of PrP-res formation in prion Fukuoka1 strain infected mouse N2a#58 cells relative to control | Mus musculus | 11 | assay format | Scientific Literature | ||
| 3. | ALA2175288 | B | Inhibition of Thermus aquaticus DNA polymerase using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate after 15 mins by telomeric repeat amplification protocol | Thermus aquaticus | 6 | assay format | Scientific Literature | ||
| 4. | ALA2175300 | B | Inhibition of tetrahymena telomerase using 3'-ACT TCG TAG AGC AGA TTG-5' as substrate at 1 uM incubated for 10 mins prior to extension reaction by telomeric repeat amplification protocol | Tetrahymena | 4 | assay format | Scientific Literature | ||
| 5. | ALA2175301 | B | Inhibition of tetrahymena telomerase using 3'-ACT TCG TAG AGC AGA TTG-5' as substrate incubated for 10 mins prior to extension reaction by telomeric repeat amplification protocol | Tetrahymena | 6 | assay format | Scientific Literature | ||
| 6. | ALA2175302 | B | Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate at 1 uM incubated for 15 mins prior to extension reaction by telomeric repeat amplification protocol | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 7. | ALA2175303 | B | Binding affinity to Stenotrophomonas sp. TSG4 5'-(GGGATT)3GGGTT-3' DNA assessed as G-quadruplex stabilization at 2 uM by thermal melt analysis | Stenotrophomonas sp. TSG4 | 6 | nucleic acid format | Scientific Literature | ||
| 8. | ALA2175309 | B | Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by telomeric repeat amplification protocol | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 9. | ALA2175310 | B | Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction followed by compound washout by spin-telomeric repeat amplification protocol | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 10. | ALA3131094 | B | Binding affinity to HIV 1 HXB2 G-quadruplex FL-LTR DNA assessed as blocking sites at G-tracts (4 to 2) after 20 mins by Taq polymerase stop assay | Human immunodeficiency virus 1 | 2 | assay format | Scientific Literature | ||
| 11. | ALA3131095 | B | Binding affinity to HIV 1 HXB2 G-quadruplex FL-LTR DNA assessed as blocking at G-tracts (6 and 5) after 20 mins by Taq polymerase stop assay | Human immunodeficiency virus 1 | 2 | assay format | Scientific Literature | ||
| 12. | ALA3131282 | B | Binding affinity to HIV 1 HXB2 G-quadruplex LTR-4 DNA assessed as change in melting temperature at 16 uM after 24 hrs by circular dichroism spectropolarimeter analysis in the presence of K+ | Human immunodeficiency virus | 3 | assay format | Scientific Literature | ||
| 13. | ALA3131283 | B | Binding affinity to HIV 1 HXB2 G-quadruplex LTR-FL DNA assessed as change in melting temperature at 16 uM after 24 hrs by circular dichroism spectropolarimeter analysis in the presence of K+ | Human immunodeficiency virus 1 | 3 | assay format | Scientific Literature | ||
| 14. | ALA3131284 | B | Binding affinity to HIV 1 HXB2 G-quadruplex LTR-3 DNA assessed as change in melting temperature at 16 uM after 24 hrs by circular dichroism spectropolarimeter analysis in the presence of K+ | Human immunodeficiency virus 1 | 3 | assay format | Scientific Literature | ||
| 15. | ALA3131285 | B | Binding affinity to HIV 1 HXB2 G-quadruplex LTR-3 DNA assessed as change in melting temperature at 16 uM after 24 hrs by circular dichroism spectropolarimeter analysis in the absence of K+ | Human immunodeficiency virus 1 | 3 | assay format | Scientific Literature | ||
| 16. | ALA3131286 | B | Binding affinity to HIV 1 HXB2 G-quadruplex LTR-2 DNA assessed as change in melting temperature at 16 uM after 24 hrs by circular dichroism spectropolarimeter analysis in the absence of K+ | Human immunodeficiency virus 1 | 3 | assay format | Scientific Literature | ||
| 17. | ALA3131288 | B | Binding affinity to HIV 1 HXB2 G-quadruplex LTR-2 DNA assessed as change in melting temperature at 16 uM after 24 hrs by circular dichroism spectropolarimeter analysis in the presence of K+ | Human immunodeficiency virus 1 | 3 | assay format | Scientific Literature | ||
| 18. | ALA3825262 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus 180 assessed as planktonic cell killing at 5 ug/ml after 15 mins followed by irradiation with paterson lamp at 100 J/cm'2 by serial ten fold dilution method | Staphylococcus aureus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA3825263 | F | Antibacterial activity against Burkholderia cepacia assessed as cell killing at 250 ug/ml after 15 mins followed by irradiation with paterson lamp at 100 J/cm'2 by serial ten fold dilution method | Burkholderia cepacia | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA3831030 | B | Binding affinity to 5'-FAM/3'-TAMRA labeled c-MYC 22-mer G-quadruplex DNA (unknown origin) assessed as change in melting temperature at 4 uM after 12 hrs by TR-FRET assay | Not specified | 16 | assay format | Scientific Literature |
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