| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2174649 | T | Neurotoxicity in C57BL/6 mouse assessed as haloperidol-induced deffect in motor coordination at 3 mg/kg, ip administered 15 mins prior to haloperidol challenge measured at 0.5 to 1 hr post haloperidol challenge | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA2174650 | T | Neurotoxicity in C57BL/6 mouse assessed as potentiation of haloperidol-induced catalepsy at 1 to 10 mg/kg, ip administered 15 mins prior to haloperidol challenge measured at 0.5 to 1 hr post haloperidol challenge | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA2174652 | T | Neurotoxicity in C57BL/6 mouse assessed as induction of catalepsy at 1 to 10 mg/kg, ip measured at 0.5 to 1 hr | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA2174653 | T | Neurotoxicity in C57BL/6 mouse assessed as induction of catalepsy at 30 mg/kg, ip measured at 0.5 to 1 hr | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA2174654 | F | Antiparkinsonian activity in C57BL/6 mouse assessed as decrease in MPTP-induced rearing behavior impairment at 30 mg/kg, ip administered 15 mins on day 7 post MPTP challenge | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA2174655 | B | Inhibition of mouse PDE7A assessed as [3H]cAMP hydrolysis after 5 to 15 mins by scintillation counter | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 7. | ALA2174656 | A | Free drug level in C57 mouse brain homogenate at 10 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA2174657 | A | Free drug level in C57 mouse brain homogenate at 100 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA2174658 | A | Free drug level in C57 mouse brain homogenate at 30 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA2174659 | A | Ratio of drug level in brain to plasma in C57 mouse at 30 mg/kg, ip after 30 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA2174660 | A | Ratio of drug level in brain to plasma in C57 mouse at 100 mg/kg, ip after 30 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA2174661 | A | Drug uptake in C57 mouse brain at 100 mg/kg, ip after 30 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA2174662 | A | Plasma concentration in C57 mouse at 100 mg/kg, ip after 30 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA2174663 | A | Drug uptake in C57 mouse brain at 30 mg/kg, ip after 30 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA2174664 | A | Plasma concentration in C57 mouse at 30 mg/kg, ip after 30 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA2174665 | A | Tmax in C57 mouse at 30 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA2174666 | A | Tmax in C57 mouse at 100 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA2174667 | A | AUC in C57 mouse at 30 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA2174668 | A | AUC in C57 mouse at 100 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA2174669 | A | Cmax in C57 mouse at 100 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!