# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2175089 | F | Cytotoxicity against human MDA-MB-435 cells incubated for 72 hrs by MTT assay | Homo sapiens | 72 | ALA2169847 | cell-based format | Scientific Literature | |
2. | ALA2175090 | F | Cytotoxicity against human HCT116 cells incubated for 72 hrs by MTT assay | Homo sapiens | 74 | ALA2169847 | cell-based format | Scientific Literature | |
3. | ALA2175091 | F | Cytotoxicity against human A549 cells incubated for 72 hrs by MTT assay | Homo sapiens | 74 | ALA2169847 | cell-based format | Scientific Literature | |
4. | ALA4729229 | B | Inhibition of human PDE5A1 (535-860 residues) expressed in Escherichia coli BL21 incubated for 15 mins using [3H]-cGMP as substrate by liquid scintillation counting method | Homo sapiens | 14 | ALA4725363 | assay format | Scientific Literature | |
5. | ALA4729230 | A | Inhibition of human PDE6C (2-854 residues) expressed in Sf9 cells incubated for 15 mins using [3H]-cGMP as substrate by liquid scintillation counting method | Homo sapiens | 5 | ALA4725363 | cell-based format | Scientific Literature | |
6. | ALA4729231 | B | Selectivity index, ratio of IC50 for human PDE6C to IC50 for human PDE5A1 | Homo sapiens | 5 | ALA4725363 | assay format | Scientific Literature |