# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2174952 | A | Time dependent inhibition of CYP2D6 | 2 | single protein format | Scientific Literature | |||
2. | ALA2174953 | A | Time dependent inhibition of CYP2C9 | 2 | single protein format | Scientific Literature | |||
3. | ALA2174954 | A | Time dependent inhibition of CYP2C19 | 2 | single protein format | Scientific Literature | |||
4. | ALA2174955 | A | Time dependent inhibition of CYP3A4 | 2 | single protein format | Scientific Literature | |||
5. | ALA2174956 | A | Time dependent inhibition of CYP1A2 | 2 | single protein format | Scientific Literature | |||
6. | ALA2174958 | A | Oral bioavailability in dog | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
7. | ALA2174959 | A | Half life in dog | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
8. | ALA2174960 | A | Oral bioavailability in rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
9. | ALA2174961 | A | Half life in rat | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
10. | ALA2174962 | A | Volume of distribution at steady state in rat | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
11. | ALA2174963 | A | Volume of distribution at steady state in dog | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
12. | ALA2174964 | A | Clearance in dog | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
13. | ALA2174965 | A | Clearance in rat | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
14. | ALA2174966 | F | Antiinflammatory activity in Balb/c mouse assessed as inhibition of anti IgD-induced activation of B cells measuring CD 86 expression at 1 mg/kg, po dosed 0.5 hrs prior to anti IgD challenge measured after 6 hrs by fluorescence-activated cell sorting method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
15. | ALA2174967 | A | Reversible inhibition of CYP2D6 | 2 | single protein format | Scientific Literature | |||
16. | ALA2174968 | A | Reversible inhibition of CYP2C9 | 2 | single protein format | Scientific Literature | |||
17. | ALA2174969 | A | Reversible inhibition of CYP2C19 | 2 | single protein format | Scientific Literature | |||
18. | ALA2174970 | A | Reversible inhibition of CYP3A4 | 2 | single protein format | Scientific Literature | |||
19. | ALA2174971 | A | Reversible inhibition of CYP1A2 | 2 | single protein format | Scientific Literature | |||
20. | ALA2174975 | B | Selectivity ratio of IC50 of PI3Kbeta to IC50 of PI3Kdelta | 1 | assay format | Scientific Literature |