# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2175187 | B | Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction in nucleus after 30 mins by EMSA | Mus musculus | 12 | ALA2169778 | cell-based format | Scientific Literature | |
2. | ALA3705990 | B | EMSA Based Assay: A screening process evaluated in vitro disruption of STAT3(dimer)-DNA formation through a previously published EMSA based assays, giving a valuable insight into the inhibitor's mode of action against the STAT3 homo-dimer. | 13 | ALA3638769 | single protein format | BindingDB Database | ||
3. | ALA5233540 | B | Inhibition of recombinant STAT3 (unknown origin) expressed in baculovirus in Sf9 insect cells assessed as reduction in DNA binding activity with NIH3T3 nuclear extract incubated for 30 mins by electrophoretic mobility shift assay | Homo sapiens | 13 | ALA5233213 | cell-based format | Scientific Literature | |
4. | ALA5233542 | F | Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell viability by WST-1 assay | Homo sapiens | 1 | ALA5233213 | cell-based format | Scientific Literature | |
5. | ALA5233543 | F | Cytotoxicity against mouse NIH3T3 cells assessed as inhibition of cell viability by WST-1 assay | Mus musculus | 1 | ALA5233213 | cell-based format | Scientific Literature |