# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2175828 | Binding | Inhibition of delta8,7-isomerase in human HL60 cells assessed as accumulation of zymostenol at 50 uM after 24 hrs by GC/MS analysis | Homo sapiens | 7 | ALA2169759 | cell-based format | Scientific Literature | |
2. | ALA2175829 | Binding | Inhibition of delta8,7-isomerase in human HL60 cells assessed as accumulation of zymostenol at 1 uM after 24 hrs by GC/MS analysis | Homo sapiens | 5 | ALA2169759 | cell-based format | Scientific Literature | |
3. | ALA2175830 | Binding | Inhibition of 7-dehydrocholesterol reductase in human HL60 cells assessed as accumulation of 7-dehydrocholesterol at 50 uM after 24 hrs by GC/MS analysis | Homo sapiens | 9 | ALA2169759 | cell-based format | Scientific Literature | |
4. | ALA2175831 | Binding | Inhibition of 7-dehydrocholesterol reductase in human HL60 cells assessed as accumulation of 7-dehydrocholesterol at 1 uM after 24 hrs by GC/MS analysis | Homo sapiens | 12 | ALA2169759 | cell-based format | Scientific Literature | |
5. | ALA2175832 | ADME | Inhibition of ergosterol synthesis in Yarrowia lipolytica DSM 1345 at 10 and 20 ug/mL after 48 hrs by GC/MS analysis | Yarrowia lipolytica | 12 | ALA2169759 | organism-based format | Scientific Literature | |
6. | ALA2175833 | ADME | Inhibition of ergosterol synthesis in Saccharomyces cerevisiae DSM 1333 at 10 and 20 ug/mL after 48 hrs by GC/MS analysis | Saccharomyces cerevisiae | 12 | ALA2169759 | organism-based format | Scientific Literature | |
7. | ALA2175834 | ADME | Inhibition of ergosterol synthesis in Candida glabrata DSM 11226 at 10 and 20 ug/mL after 48 hrs by GC/MS analysis | Nakaseomyces glabratus | 12 | ALA2169759 | organism-based format | Scientific Literature | |
8. | ALA2175835 | ADME | Antifungal activity against Yarrowia lipolytica DSM 1345 after 48 hrs | Yarrowia lipolytica | 13 | ALA2169759 | organism-based format | Scientific Literature | |
9. | ALA2175836 | ADME | Antimicrobial activity against Saccharomyces cerevisiae DSM 1333 after 48 hrs | Saccharomyces cerevisiae | 13 | ALA2169759 | organism-based format | Scientific Literature | |
10. | ALA2175837 | ADME | Antifungal activity against Candida glabrata DSM 11226 after 48 hrs | Nakaseomyces glabratus | 13 | ALA2169759 | organism-based format | Scientific Literature | |
11. | ALA2175838 | ADME | Antifungal activity against Yarrowia lipolytica DSM 1345 after 36 hrs by disc diffusion method | Yarrowia lipolytica | 12 | ALA2169759 | organism-based format | Scientific Literature | |
12. | ALA2175839 | ADME | Antifungal activity against Saccharomyces cerevisiae DSM 1333 after 36 hrs by disc diffusion method | Saccharomyces cerevisiae | 12 | ALA2169759 | organism-based format | Scientific Literature | |
13. | ALA2175840 | ADME | Antifungal activity against Hyphopichia burtonii DSM 11226 after 36 hrs by disc diffusion method | Hyphopichia burtonii | 12 | ALA2169759 | assay format | Scientific Literature | |
14. | ALA2176287 | ADME | Antifungal activity against Candida glabrata DSM 11226 after 36 hrs by disc diffusion method | Nakaseomyces glabratus | 12 | ALA2169759 | organism-based format | Scientific Literature | |
15. | ALA2176288 | ADME | Antifungal activity against Aspergillus brasiliensis DSM 1988 after 36 hrs by disc diffusion method | Aspergillus brasiliensis | 12 | ALA2169759 | assay format | Scientific Literature | |
16. | ALA2176289 | ADME | Antibacterial activity against Streptococcus entericus DSM 14446 after 36 hrs by disc diffusion method | Streptococcus entericus | 12 | ALA2169759 | assay format | Scientific Literature | |
17. | ALA2176290 | ADME | Antibacterial activity against Staphylococcus equorum DSM 20675 after 36 hrs by disc diffusion method | Staphylococcus equorum | 12 | ALA2169759 | assay format | Scientific Literature | |
18. | ALA2176291 | ADME | Antibacterial activity against Pseudomonas antimicrobica DSM 8361 after 36 hrs by disc diffusion method | Burkholderia gladioli | 12 | ALA2169759 | assay format | Scientific Literature | |
19. | ALA2176292 | ADME | Antibacterial activity against Escherichia coli DSM 426 after 36 hrs by disc diffusion method | Escherichia coli | 12 | ALA2169759 | organism-based format | Scientific Literature | |
20. | ALA2176293 | ADME | Cytotoxicity against human HL60 cells after 24 hrs by MTT assay | Homo sapiens | 12 | ALA2169759 | cell-based format | Scientific Literature |