| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2176294 | B | Inhibition of NADH oxidase activity in bovine heart sub-mitochondrial particles assessed as remaining enzyme activity at 1 uM by spectrophotometry relative to untreated control | Bos taurus | 7 | assay format | Scientific Literature | ||
| 2. | ALA2176295 | B | Inhibition of NADH oxidase activity in bovine heart sub-mitochondrial particles assessed as remaining enzyme activity at 5 uM by spectrophotometry relative to untreated control | Bos taurus | 7 | assay format | Scientific Literature | ||
| 3. | ALA2176296 | F | Cytoprotection in diethyl maleate-treated human Friedreich's ataxia lymphocytes incubated for 17 hrs before diethyl maleate challenge by trypan blue dye exclusion method | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 4. | ALA2176297 | F | Cytoprotection in diethyl maleate-treated human CCRF-CEM cells 2.5 uM incubated for 17 hrs before diethyl maleate challenge by trypan blue dye exclusion method (Rvb = 18 +/- 10%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 5. | ALA2176298 | F | Cytoprotection in diethyl maleate-treated human CCRF-CEM cells 0.5 uM incubated for 17 hrs before diethyl maleate challenge by trypan blue dye exclusion method (Rvb = 18 +/- 10%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 6. | ALA2176405 | F | Cytoprotection in diethyl maleate-treated human CCRF-CEM cells 0.1 uM incubated for 17 hrs before diethyl maleate challenge by trypan blue dye exclusion method (Rvb = 18 +/- 10%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA2176406 | F | Preservation of mitochondrial membrane potential in diethyl maleate-treated human Friedreich's ataxia lymphocytes at 2.5 uM pre-incubated for 16 hrs before diethyl maleate challenge by FACS method (Rvb = 25%) | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 8. | ALA2176407 | F | Preservation of mitochondrial membrane potential in diethyl maleate-treated human Friedreich's ataxia lymphocytes at 1 uM pre-incubated for 16 hrs before diethyl maleate challenge by FACS method (Rvb = 25%) | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 9. | ALA2176408 | F | Preservation of mitochondrial membrane potential in diethyl maleate-treated human Friedreich's ataxia lymphocytes at 0.5 uM pre-incubated for 16 hrs before diethyl maleate challenge by FACS method (Rvb = 25%) | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 10. | ALA2176409 | F | Inhibition of diethyl maleate-induced ROS production in human CCRF-CEM cells at 0.25 to 2.5 uM incubated for 16 hrs by DCFH-DA dye staining based FACS method | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 11. | ALA2176410 | F | Inhibition of lipid peroxidation in diethyl maleate-treated human Friedreich's ataxia lymphocytes at 5 uM pre-incubated for 16 hrs before diethyl maleate challenge by FACS method relative to untreated control | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 12. | ALA2176411 | F | Inhibition of lipid peroxidation in diethyl maleate-treated human Friedreich's ataxia lymphocytes at 2.5 uM pre-incubated for 16 hrs before diethyl maleate challenge by FACS method relative to untreated control | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 13. | ALA2176412 | B | Inhibition of NADH oxidase activity in bovine heart sub-mitochondrial particles assessed as remaining enzyme activity at 10 uM by spectrophotometry relative to untreated control | Bos taurus | 7 | assay format | Scientific Literature | ||
| 14. | ALA2401418 | B | Inhibition of NADH-ubiquinone oxidoreductase in bovine heart mitochondria after 5 mins by spectrophotometric analysis relative to control | Bos taurus | 4 | mitochondrion format | Scientific Literature | ||
| 15. | ALA2401419 | B | Inhibition of NADH-ubiquinone oxidoreductase in bovine heart mitochondria after 5 mins by spectrophotometric analysis | Bos taurus | 5 | mitochondrion format | Scientific Literature | ||
| 16. | ALA2401420 | B | Inhibition of NADH oxidase activity of bovine heart mitochondrial complexes 1, 2 and 3 at 10 uM after 5 mins by spectrophotometric analysis relative to control | Bos taurus | 5 | assay format | Scientific Literature | ||
| 17. | ALA2401421 | B | Inhibition of NADH oxidase activity of bovine heart mitochondrial complexes 1, 2 and 3 at 5 uM after 5 mins by spectrophotometric analysis relative to control | Bos taurus | 5 | assay format | Scientific Literature | ||
| 18. | ALA2401422 | B | Inhibition of NADH oxidase activity of bovine heart mitochondrial complexes 1, 2 and 3 at 1 uM after 5 mins by spectrophotometric analysis relative to control | Bos taurus | 5 | assay format | Scientific Literature | ||
| 19. | ALA2401423 | F | Effect on total ATP level in Friedreich's ataxia disease patient GM15850 cells at 25 uM after 48 hrs by bioluminescence assay relative to control | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 20. | ALA2401424 | F | Effect on total ATP level in Friedreich's ataxia disease patient GM15850 cells at 10 uM after 48 hrs by bioluminescence assay relative to control | Homo sapiens | 5 | assay format | Scientific Literature |
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