# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2175269 | F | Ratio of isoginkgetin IC50 to compound IC50 for axenically grown Leishmania donovani amastigotes | Leishmania donovani | 1 | ALA2169835 | organism-based format | Scientific Literature | |
2. | ALA2175272 | A | Therapeutic index, ratio of IC50 for mouse Peritoneal macrophages to IC50 for SSG-resistant Leishmania donovani 39 amastigote infected in mouse peritoneal macrophages | 21 | ALA2169835 | assay format | Scientific Literature | ||
3. | ALA2175276 | F | Antimicrobial activity against SSG-resistant Leishmania donovani 39 amastigote infected in mouse peritoneal macrophages assessed as inhibition of parasite growth at 5 uM after 3 days by Giemsa staining method | Leishmania donovani | 1 | ALA2169835 | organism-based format | Scientific Literature | |
4. | ALA2175393 | A | Therapeutic index, ratio of IC50 for mouse Peritoneal macrophages to IC50 for SSG-resistant Leishmania donovani 39 promastigote | 8 | ALA2169835 | assay format | Scientific Literature | ||
5. | ALA2175394 | A | Therapeutic index, ratio of IC50 for mouse Peritoneal macrophages to IC50 for pentamidine-resistant Leishmania donovani AG83PentR50 promastigote | 8 | ALA2169835 | assay format | Scientific Literature | ||
6. | ALA2175395 | A | Therapeutic index, ratio of IC50 for mouse PEM cells to IC50 for wild-type Leishmania donovani AG83 promastigote | 8 | ALA2169835 | cell-based format | Scientific Literature | ||
7. | ALA2175396 | A | Cytotoxicity against mouse Peritoneal macrophages cells after 72 hrs by MTS assay | Mus musculus | 40 | ALA2169835 | cell-based format | Scientific Literature | |
8. | ALA2175397 | A | Cytotoxicity against mouse RAW264.7 cells after 72 hrs by MTS assay | Mus musculus | 70 | ALA2169835 | cell-based format | Scientific Literature | |
9. | ALA2175398 | F | Antimicrobial activity against SSG-resistant Leishmania donovani 39 amastigote infected in mouse peritoneal macrophages assessed as inhibition of parasite growth after 72 hrs by Giemsa staining method | Leishmania donovani | 20 | ALA2169835 | organism-based format | Scientific Literature | |
10. | ALA2175399 | F | Antimicrobial activity against pentamidine-resistant Leishmania donovani AG83PentR50 promastigote assessed as inhibition of parasite growth after 72 hrs by MTS assay | Leishmania donovani | 70 | ALA2169835 | organism-based format | Scientific Literature | |
11. | ALA2175841 | F | Antimicrobial activity against SSG-resistant Leishmania donovani 39 promastigote assessed as inhibition of parasite growth after 72 hrs by MTS assay | Leishmania donovani | 70 | ALA2169835 | organism-based format | Scientific Literature | |
12. | ALA2175842 | F | Antimicrobial activity against wild-type Leishmania donovani AG83 promastigote assessed as inhibition of parasite growth after 72 hrs by MTS assay | Leishmania donovani | 70 | ALA2169835 | organism-based format | Scientific Literature | |
13. | ALA2212546 | B | Inhibition of P-gp-mediated paclitaxel resistance in human LCC6MDR cells assessed as fold decrease in paclitaxel IC50 for cytotoxic activity at 1 uM after 5 days by MTS assay relative to parental cells | Homo sapiens | 40 | ALA2203168 | cell-based format | Scientific Literature | |
14. | ALA2214988 | B | Inhibition of P-gp-mediated paclitaxel resistance in human LCC6MDR cells assessed as fold decrease in paclitaxel IC50 for cytotoxic activity at 0.5 uM after 5 days by MTS assay relative to parental cells | Homo sapiens | 39 | ALA2203168 | cell-based format | Scientific Literature | |
15. | ALA2214989 | F | Cytotoxicity against human MDA435/LCC6MDR cells expressing MDR after 72 hrs | Homo sapiens | 40 | ALA2203168 | cell-based format | Scientific Literature | |
16. | ALA2214990 | F | Cytotoxicity against human LCC-6 cells after 72 hrs | Homo sapiens | 40 | ALA2203168 | cell-based format | Scientific Literature | |
17. | ALA2214991 | A | Cytotoxicity against mouse L929 cells after 72 hrs | Mus musculus | 40 | ALA2203168 | cell-based format | Scientific Literature | |
18. | ALA3367273 | F | Leishmanicidal activity against Leishmania | Leishmania | 1 | ALA3351502 | organism-based format | Scientific Literature |