| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2182243 | B | Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysis | Mus musculus | 11 | cell-based format | Scientific Literature | ||
| 2. | ALA2182244 | A | Apparent permeability across human Caco2 cells at 10 um after 2 hrs by LC/MS/MS analysis | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 3. | ALA2182245 | P | Thermodynamic solubility of the compound in DMSO solution after 24 hrs by shake flask method | 24 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA2182246 | B | Selectivity ratio of Ki for CDK1/cyclin E to Ki for human recombinant GSK3beta | Homo sapiens | 30 | assay format | Scientific Literature | ||
| 5. | ALA2182637 | B | Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity assay | Homo sapiens | 30 | single protein format | Scientific Literature | ||
| 6. | ALA2182638 | B | Inhibition of CDK2/cyclin E expressed in baculovirus infected insect cells using [gamma33P]ATP after 60 mins by scintillation proximity assay | 30 | cell-based format | Scientific Literature | |||
| 7. | ALA3301363 | P | ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5 | 4,197 | small-molecule physicochemical format | AstraZeneca Deposited Data | |||
| 8. | ALA3301364 | P | ASTRAZENECA: Solubility in pH7.4 buffer using solid starting material using the method described in J. Assoc. Lab. Autom. 2011, 16, 276-284. Experimental range 0.10 to 1500 uM | 1,763 | small-molecule physicochemical format | AstraZeneca Deposited Data |
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