# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2185176 | F | Agonist activity at human nAChR alpha6/alpha3beta2beta3 V273S mutant expressed in HEK293T cells by FLIPR | Homo sapiens | 7 | ALA2176949 | cell-based format | Scientific Literature | |
2. | ALA2187043 | F | Agonist activity at human nAChR alpha6/alpha3beta2beta3 V273S mutant expressed in HEK293T cells by FLIPR relative to 10 uM nicotine | Homo sapiens | 7 | ALA2176949 | cell-based format | Scientific Literature | |
3. | ALA2187459 | F | Agonist activity at alpha6/alpha3beta2beta3 nAChR in Sprague-Dawley rat striatal synaptosomes assessed as induction of dopamine release | Rattus norvegicus | 7 | ALA2176949 | subcellular format | Scientific Literature | |
4. | ALA2187460 | B | Displacement of [125I]epibatidine from human alpha6/alpha3beta2beta3 nAChR expressed in HEK293T cells | Homo sapiens | 7 | ALA2176949 | cell-based format | Scientific Literature | |
5. | ALA2187461 | F | Agonist activity at alpha6/alpha3beta2beta3 nAChR in Sprague-Dawley rat striatal synaptosomes assessed as induction of dopamine release relative to 10 uM nicotine | Rattus norvegicus | 7 | ALA2176949 | subcellular format | Scientific Literature | |
6. | ALA2187462 | F | Agonist activity at rat alpha7 nAChR T6'S59 mutant expressed in rat GH4C1 cells by whole cell voltage clamp based electrophysiology method | Rattus norvegicus | 7 | ALA2176949 | cell-based format | Scientific Literature | |
7. | ALA2187463 | F | Agonist activity at rat alpha7 nAChR T6'S59 mutant expressed in rat GH4C1 cells by whole cell voltage clamp based electrophysiology method relative to 1 mM acetylcholine | Rattus norvegicus | 7 | ALA2176949 | cell-based format | Scientific Literature | |
8. | ALA2187464 | F | Agonist activity at human alpha4beta2 nAChR expressed in human SH-EP1 cells by whole cell voltage clamp based electrophysiology method | Homo sapiens | 7 | ALA2176949 | cell-based format | Scientific Literature | |
9. | ALA2187465 | F | Agonist activity at human alpha4beta2 nAChR expressed in human SH-EP1 cells by whole cell voltage clamp based electrophysiology method relative to 1 mM acetylcholine | Homo sapiens | 7 | ALA2176949 | cell-based format | Scientific Literature | |
10. | ALA2187466 | F | Agonist activity at human alpha3beta4 nAChR expressed in human SH-SY5Y cells assessed as increase in calcium flux by FLIPR | Homo sapiens | 25 | ALA2176949 | cell-based format | Scientific Literature | |
11. | ALA2187467 | F | Agonist activity at human alpha3beta4 nAChR expressed in human SH-SY5Y cells assessed as increase in calcium flux by FLIPR relative to 10 uM nicotine | Homo sapiens | 25 | ALA2176949 | cell-based format | Scientific Literature | |
12. | ALA2187468 | F | Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPR | Homo sapiens | 25 | ALA2176949 | cell-based format | Scientific Literature | |
13. | ALA2187469 | F | Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPR relative to 10 uM nicotine | Homo sapiens | 25 | ALA2176949 | cell-based format | Scientific Literature | |
14. | ALA2187470 | F | Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPR | Homo sapiens | 25 | ALA2176949 | cell-based format | Scientific Literature | |
15. | ALA2187471 | F | Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPR relative to 10 uM nicotine | Homo sapiens | 25 | ALA2176949 | cell-based format | Scientific Literature | |
16. | ALA2187475 | B | Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in human SH-SY5Y cells | Homo sapiens | 53 | ALA2176949 | cell-based format | Scientific Literature | |
17. | ALA2187476 | B | Displacement of [3H]epibatidine from human alpha7 nAChR expressed in human HEK/RIC3 cells | Homo sapiens | 53 | ALA2176949 | cell-based format | Scientific Literature | |
18. | ALA2187477 | B | Displacement of [3H]nicotine from human alpha4beta2 nAChR expressed in human SH-EP1 cells | Homo sapiens | 53 | ALA2176949 | cell-based format | Scientific Literature |