# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2189035 | F | Prevention of apoptosis in rat H9c2 cells assessed as protection against oxidative stress-induced cytotoxicity at 100 nM pM by Alamar blue assay | Rattus norvegicus | 26 | cell-based format | Scientific Literature | ||
2. | ALA2189036 | F | Prevention of apoptosis in rat H9c2 cells assessed as reduction in fall of mitochondrial membrane potential at 100 nM after 1 hr | Rattus norvegicus | 26 | cell-based format | Scientific Literature | ||
3. | ALA2189037 | A | Cytotoxicity against rat H9c2 cells assessed as cell viability in absence of H2O2 | Rattus norvegicus | 26 | cell-based format | Scientific Literature | ||
4. | ALA2189039 | F | Antioxidant activity of the compound assessed as DPPH radical scavenging at 10 uM after 30 secs by spectrophotometry | 32 | assay format | Scientific Literature | |||
5. | ALA2189040 | F | Antioxidant activity assessed as scavenging of morpholino sydononimine based nitric oxide release by chemiluminescence assay | 32 | assay format | Scientific Literature | |||
6. | ALA2189044 | F | Antioxidant activity assessed as scavenging of glucose oxidase-generated H2O2 and hydroxyl radicals by chemiluminescence assay | 32 | assay format | Scientific Literature | |||
7. | ALA2189045 | B | Selectivity ratio of IC50 for equine BuChE to IC50 for bovine AChE | 27 | assay format | Scientific Literature | |||
8. | ALA2189046 | B | Inhibition of equine BuChE after 120 mins by Ellman's method | Equus caballus | 29 | single protein format | Scientific Literature | ||
9. | ALA2189047 | B | Inhibition of bovine AChE after 120 mins by Ellman's method | Bos taurus | 29 | single protein format | Scientific Literature | ||
10. | ALA3267163 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced NaNO2 release at >=10 pM treated for 30 mins prior to LPS challenge measured after 24 hrs by griess reaction assay | Mus musculus | 5 | cell-based format | Scientific Literature | ||
11. | ALA3267164 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced NaNO2 release at 10 pM treated for 30 mins prior to LPS challenge measured after 24 hrs by griess reaction assay relative to budesonide | Mus musculus | 5 | cell-based format | Scientific Literature | ||
12. | ALA3267166 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced NaNO2 release at 10 pM treated for 30 mins prior to LPS challenge measured after 24 hrs by griess reaction assay relative to melatonin | Mus musculus | 5 | cell-based format | Scientific Literature | ||
13. | ALA3267169 | F | Antiinflammatory activity in C57bl/6 mouse peritoneal macrophages assessed as reduction in LPS-induced TNF-alpha production at >=1 pM treated for 30 mins prior to LPS challenge measured after 6 hrs by ELISA | Mus musculus | 5 | cell-based format | Scientific Literature | ||
14. | ALA3267492 | F | Antiinflammatory activity in C57bl/6 mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production at >=1 nM treated for 30 mins prior to LPS challenge measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
15. | ALA3267493 | A | Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 10 pM to 10 uM by MTT assay | Mus musculus | 11 | cell-based format | Scientific Literature | ||
16. | ALA3267494 | A | Cytotoxicity against C57bl/6 mouse peritoneal macrophages assessed as cell viability at 10 pM to 10 uM by MTT assay | Mus musculus | 11 | cell-based format | Scientific Literature | ||
17. | ALA3267499 | B | Inhibition of AChE in bovine erythrocytes using acetylthiocholine iodide as substrate by Ellman's method | Bos taurus | 11 | cell-based format | Scientific Literature | ||
18. | ALA3267500 | B | Inhibition of BuChE in equine serum using butylthiocholine iodide as substrate by Ellman's method | Equus caballus | 11 | single protein format | Scientific Literature |