# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2183226 | B | Inhibition of human recombinant Top1-mediated DNA cleavage after 20 mins by SDS-PAGE analysis relative to camptothecin | Homo sapiens | 12 | single protein format | Scientific Literature | ||
2. | ALA2183227 | F | Antiproliferative activity against human DU145 cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
3. | ALA2183228 | F | Antiproliferative activity against human MCF7 cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
4. | ALA2183229 | F | Antiproliferative activity against human SN12C cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
5. | ALA2183230 | F | Antiproliferative activity against human UACC62 cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
6. | ALA2183231 | F | Antiproliferative activity against human OVCAR3 cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
7. | ALA2183232 | F | Antiproliferative activity against human SF539 cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
8. | ALA2183233 | F | Antiproliferative activity against human HCT116 cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
9. | ALA2183234 | F | Antiproliferative activity against human HOP62 cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
10. | ALA3419863 | F | Cytotoxicity against human 22Rv1 cells after 2 hrs by [3H]thymidine incorporation assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA3419865 | F | Antitumor activity against human 22Rv1 cells xenografted in nu/nu mouse assessed as regression of tumor growth at 2 umol/kg, ip administered as single dose on alternative days, 3 days/week for 3 weeks | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
12. | ALA3419867 | T | Toxicity in human 22Rv1 cells xenografted nu/nu mouse at 2 umol/kg, ip administered as single dose on alternative days, 3 days/week for 3 weeks | Mus musculus | 2 | organism-based format | Scientific Literature | ||
13. | ALA3419868 | T | Toxicity in human 22Rv1 cells xenografted nu/nu mouse assessed as induction of mouse death at 2 umol/kg, ip administered as single dose on alternative days, 3 days/week for 3 weeks | Mus musculus | 2 | organism-based format | Scientific Literature | ||
14. | ALA3419869 | T | Toxicity in human 22Rv1 cells xenografted nu/nu mouse assessed as effect on body weight at 2 umol/kg, ip administered as single dose on alternative days, 3 days/week for 3 weeks | Mus musculus | 2 | organism-based format | Scientific Literature | ||
15. | ALA3423834 | B | Inhibition of human recombinant TDP1 assessed as hydrolysis of N14Y to N14P after 15 mins by PAGE analysis | Homo sapiens | 27 | single protein format | Scientific Literature |