#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2187115	A	Free drug concentration in C57BL/6 mouse brain at 300 umol/kg, po at 1.5 hrs	Mus musculus	4		organism-based format	Scientific Literature
2.	ALA2187121	A	Free drug concentration in C57BL/6 mouse plasma at 300 umol/kg, po at 1.5 hrs	Mus musculus	4		organism-based format	Scientific Literature
3.	ALA2187536	F	Antialzheimer activity in C57BL/6 mouse assessed as reduction in sAPPbeta level in brain at 300 umol/kg, po	Mus musculus	4		organism-based format	Scientific Literature
4.	ALA2187542	F	Antialzheimer activity in C57BL/6 mouse assessed as reduction in amyloid beta 42 level in brain at 300 umol/kg, po	Mus musculus	4		organism-based format	Scientific Literature
5.	ALA2187550	A	Fraction unbound in C57BL/6 mouse brain at 300 umol/kg, po	Mus musculus	4		organism-based format	Scientific Literature
6.	ALA2187556	A	Fraction unbound in C57BL/6 mouse plasma at 300 umol/kg, po	Mus musculus	4		organism-based format	Scientific Literature
7.	ALA2187562	F	Antialzheimer activity in C57BL/6 mouse assessed as reduction in amyloid beta 40 level in brain at 300 umol/kg, po at 1.5 hrs by ELISA relative to control	Mus musculus	4		organism-based format	Scientific Literature
8.	ALA2187563	B	Inhibition of BACE1-mediated amyloid beta 40 release in C57/BL6 mouse primary cortical neurons after overnight incubation by ELISA	Mus musculus	9		single protein format	Scientific Literature
9.	ALA2182698	B	Inhibition of human recombinant BACE2 using (europium)CEVNLDAEFK(Qsy7) as substrate incubated for 10 mins prior to substrate addition measured after 15 mins by TR-FRET assay	Homo sapiens	9		single protein format	Scientific Literature
10.	ALA2182702	P	Lipophilicity, log D of the compound by RP-HPLC analysis		27		small-molecule physicochemical format	Scientific Literature
11.	ALA2182704	P	Dissociation constant, pKa of the compound by pressure-assisted capillary electrophoretic analysis		27		small-molecule physicochemical format	Scientific Literature
12.	ALA2182705	A	Intrinsic clearance in rat hepatocytes assessed per 10'6 cells	Rattus norvegicus	27		cell-based format	Scientific Literature
13.	ALA2182706	B	Inhibition of human ERG expressed in CHO cells by IonWorks assay	Homo sapiens	27		cell-based format	Scientific Literature
14.	ALA2182707	A	Efflux ratio of apparent permeability from basal to apical to apical to basal side of human Caco2 cells at 10 uM after 60 mins by LC/MS analysis	Homo sapiens	27		cell-based format	Scientific Literature
15.	ALA2182708	A	Apparent permeability from apical to basal side of human Caco2 cells at 10 uM after 60 mins by LC/MS analysis	Homo sapiens	27		cell-based format	Scientific Literature
16.	ALA2183078	B	Inhibition of BACE1 in human SH-SY5Y cells assessed as inhibition of sAPPbeta release after 16 hrs by immunoassay	Homo sapiens	28		cell-based format	Scientific Literature
17.	ALA2183079	B	Inhibition of human recombinant BACE1 using (europium)CEVNLDAEFK(Qsy7) as substrate incubated for 10 mins prior to substrate addition measured after 15 mins by TR-FRET assay	Homo sapiens	27		single protein format	Scientific Literature
18.	ALA3531478	A	Activity of human recombinant CYP3A4 expressed in insect BTI-TN-5B1-4 cell microsomes assessed as enzyme-mediated drug metabolism measured as 2-(3-amino-4-fluoro-1-(pyridin-4-yl)-1H-isoindol-1-yl)-4-(pyrimidin-5-yl)phenol level at 2 uM after 30 mins	Homo sapiens	1		cell-based format	Scientific Literature
19.	ALA3531575	A	Drug metabolism in Sprague-Dawley rat liver microsomes assessed as GSH conjugate formation at 10 uM by LC-MS analysis	Rattus norvegicus	1		assay format	Scientific Literature
20.	ALA3531576	A	Activity of human recombinant CYP3A4 expressed in insect BTI-TN-5B1-4 cell microsomes assessed as enzyme-mediated drug metabolism measured as 4-(3-amino-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-1-yl)pyridine 1-oxide level at 2 uM after 30 mins	Homo sapiens	1		cell-based format	Scientific Literature