#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2187112	A	Free drug concentration in C57BL/6 mouse brain at 75 umol/kg, po at 1.5 hrs	Mus musculus	1		organism-based format	Scientific Literature
2.	ALA2187118	A	Free drug concentration in C57BL/6 mouse plasma at 75 umol/kg, po at 1.5 hrs	Mus musculus	1		organism-based format	Scientific Literature
3.	ALA2187533	F	Antialzheimer activity in C57BL/6 mouse assessed as reduction in sAPPbeta level in brain at 75 umol/kg, po	Mus musculus	1		organism-based format	Scientific Literature
4.	ALA2187539	F	Antialzheimer activity in C57BL/6 mouse assessed as reduction in amyloid beta 42 level in brain at 75 umol/kg, po	Mus musculus	1		organism-based format	Scientific Literature
5.	ALA2187547	A	Fraction unbound in C57BL/6 mouse brain at 75 umol/kg, po	Mus musculus	1		organism-based format	Scientific Literature
6.	ALA2187553	A	Fraction unbound in C57BL/6 mouse plasma at 75 umol/kg, po	Mus musculus	1		organism-based format	Scientific Literature
7.	ALA2187559	F	Antialzheimer activity in C57BL/6 mouse assessed as reduction in amyloid beta 40 level in brain at 75 umol/kg, po at 1.5 hrs by ELISA relative to control	Mus musculus	1		organism-based format	Scientific Literature
8.	ALA2187563	B	Inhibition of BACE1-mediated amyloid beta 40 release in C57/BL6 mouse primary cortical neurons after overnight incubation by ELISA	Mus musculus	9		single protein format	Scientific Literature
9.	ALA2182698	B	Inhibition of human recombinant BACE2 using (europium)CEVNLDAEFK(Qsy7) as substrate incubated for 10 mins prior to substrate addition measured after 15 mins by TR-FRET assay	Homo sapiens	9		single protein format	Scientific Literature
10.	ALA2182699	B	Inhibition of notch		17		assay format	Scientific Literature
11.	ALA2182702	P	Lipophilicity, log D of the compound by RP-HPLC analysis		27		small-molecule physicochemical format	Scientific Literature
12.	ALA2182704	P	Dissociation constant, pKa of the compound by pressure-assisted capillary electrophoretic analysis		27		small-molecule physicochemical format	Scientific Literature
13.	ALA2182705	A	Intrinsic clearance in rat hepatocytes assessed per 10'6 cells	Rattus norvegicus	27		cell-based format	Scientific Literature
14.	ALA2182706	B	Inhibition of human ERG expressed in CHO cells by IonWorks assay	Homo sapiens	27		cell-based format	Scientific Literature
15.	ALA2182707	A	Efflux ratio of apparent permeability from basal to apical to apical to basal side of human Caco2 cells at 10 uM after 60 mins by LC/MS analysis	Homo sapiens	27		cell-based format	Scientific Literature
16.	ALA2182708	A	Apparent permeability from apical to basal side of human Caco2 cells at 10 uM after 60 mins by LC/MS analysis	Homo sapiens	27		cell-based format	Scientific Literature
17.	ALA2183078	B	Inhibition of BACE1 in human SH-SY5Y cells assessed as inhibition of sAPPbeta release after 16 hrs by immunoassay	Homo sapiens	28		cell-based format	Scientific Literature
18.	ALA2183079	B	Inhibition of human recombinant BACE1 using (europium)CEVNLDAEFK(Qsy7) as substrate incubated for 10 mins prior to substrate addition measured after 15 mins by TR-FRET assay	Homo sapiens	27		single protein format	Scientific Literature
19.	ALA3301365	A	ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with whole human plasma at 37C for >5hrs. Method described in B. Testa et al (Eds.), Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies, Wiley-VCH, Weinheim, 2006, pp.119-141. Experimental range 10% to 99.95% bound.	Homo sapiens	1,614		cell-free format	AstraZeneca Deposited Data
20.	ALA3301368	A	ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with whole mouse plasma at 37C for >5hrs. Method described in B. Testa et al (Eds.), Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies, Wiley-VCH, Weinheim, 2006, pp.119-141. Experimental range 10% to 99.95% bound.	Mus musculus	162		cell-free format	AstraZeneca Deposited Data