| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2185136 | U | Selectivity ratio of EC50 of wild type Toxoplasma gondii to EC50 of Toxoplasma gondii expressing Cryptosporidium parvum IMPDH | Toxoplasma gondii | 32 | organism-based format | Scientific Literature | ||
| 2. | ALA2185137 | F | Antiparasitic activity against Toxoplasma gondii expressing Cryptosporidium parvum IMPDH and co-expressing yellow fluorescent protein infected to human TERT immobilized human foreskin fibroblasts assessed as parasite growth inhibition for 6 to 7 days by fluorescence based assay | Toxoplasma gondii | 32 | organism-based format | Scientific Literature | ||
| 3. | ALA2185138 | A | Toxicity against wild type Toxoplasma gondii expressing yellow fluorescent protein infected in human TERT immobilized human foreskin fibroblasts assessed as parasite growth inhibition for 6 to 7 days by fluorescence based assay | Toxoplasma gondii | 32 | organism-based format | Scientific Literature | ||
| 4. | ALA2185139 | A | Half life in mouse plasma | Mus musculus | 9 | cell-free format | Scientific Literature | ||
| 5. | ALA2185140 | A | Half life in mouse liver microsomes | Mus musculus | 9 | microsome format | Scientific Literature | ||
| 6. | ALA2185141 | B | Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid free BSA incubated for 5 mins by fluorescence based assay | Cryptosporidium parvum | 44 | assay format | Scientific Literature | ||
| 7. | ALA2185142 | B | Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluorescence based assay | Cryptosporidium parvum | 45 | assay format | Scientific Literature | ||
| 8. | ALA3362456 | B | Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometry | Bacillus anthracis | 6 | single protein format | Scientific Literature | ||
| 9. | ALA3362457 | B | Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometry | Cryptosporidium | 6 | single protein format | Scientific Literature | ||
| 10. | ALA3362471 | B | Non-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometry | Cryptosporidium | 4 | single protein format | Scientific Literature | ||
| 11. | ALA3362472 | B | Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometry | Bacillus anthracis | 6 | single protein format | Scientific Literature |
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