| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2183206 | F | Reduction in serum triglyceride level in human on standardized mixed meal diet at 5 mg UID | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA2183207 | A | Terminal half life in human at 1 to 20 mg | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA2183208 | A | Tmax in human at 1 to 20 mg | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA2183209 | F | Inhibition of adipose triacylglycerol synthesis in 14 hrs fasted Han-Wistar rat assessed as decrease in ratio of [3H]palmitic acid incorporation in to TAG and DAG at 8 mg/kg administered orally and measured 1.5 hrs post dose relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA2183210 | F | Inhibition of plasma triacylglycerol excursion in 14 hrs fasted Han-Wistar rat at administered orally 2 hrs before bolus corn oil administration measured 1.5 hrs post corn oil challenge by oral lipid tolerance test relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA2183213 | B | Inhibition of PDE10A1 receptor | 1 | single protein format | Scientific Literature | |||
| 7. | ALA2183214 | B | Inhibition of muscarinic M2 receptor | 1 | single protein format | Scientific Literature | |||
| 8. | ALA2183215 | B | Inhibition of FAAH | 1 | single protein format | Scientific Literature | |||
| 9. | ALA2183216 | B | Inhibition of ACAT at 10 uM | 1 | single protein format | Scientific Literature | |||
| 10. | ALA2183217 | A | Oral bioavailability in Beagle dog at 27.2 uM/kg | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA2183218 | A | Half life in Beagle dog at 27.2 uM/kg, po | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA2183219 | A | Volume of distribution in Beagle dog at 27.2 uM/kg, po or 1.4 uM/kg, iv | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA2183220 | A | Clearance in Beagle dog at 27.2 uM/kg, po or 1.4 uM/kg, iv | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA2183221 | A | Volume of distribution in Han-Wistar rat at 5.4 uM/kg, po or 2.7 uM/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA2183222 | A | Clearance in Han-Wistar rat at 5.4 uM/kg, po or 2.7 uM/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA2183569 | A | Oral bioavailability in C57BL/6 mouse at 8.16 uM/kg | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA2183570 | A | Half life in C57BL/6 mouse at 8.16 uM/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA2183571 | A | Intrinsic clearance in dog hepatocytes assessed as parent compound disappearance at 1 uM per 10'6 cells | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA2183572 | A | Intrinsic clearance in mouse hepatocytes assessed as parent compound disappearance at 1 uM per 10'6 cells | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA2183573 | P | Photostability stability by Hanau sun test | 1 | small-molecule physicochemical format | Scientific Literature |
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