#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2185357	B	Binding affinity to human recombinant biotinylated receptor for advanced glycation end product expressed in Escherichia coli DE3 after 1 min by surface plasmon resonance assay	Homo sapiens	1	ALA2176979	assay format	Scientific Literature
2.	ALA2185358	T	Toxicity against transgenic mouse expressing PS1/APP swedish mutant assessed as lethality at 50 mg/kg/day, po administered for 3 months measured after 2 months	Mus musculus	1	ALA2176979	organism-based format	Scientific Literature
3.	ALA2185359	F	Procognitive activity in transgenic mouse expressing PS1/APP swedish mutant assessed as spontaneous alteration at 50 mg/kg/day, po administered for 3 months measured after 2 months by Y maze test (Rvb = 50.95 +/- 10.8%)	Mus musculus	1	ALA2176979	organism-based format	Scientific Literature
4.	ALA2185360	F	Antialzheimer activity in transgenic mouse expressing PS1/APP swedish mutant assessed as insoluble amyloid beta (1 to 42) level per mg of protein in brain at 50 mg/kg/day, po for 3 months by ELISA (Rvb = 513.73 +/- 219.56 ng per mg of protein)	Mus musculus	1	ALA2176979	organism-based format	Scientific Literature
5.	ALA2185361	F	Antialzheimer activity in transgenic mouse expressing PS1/APP swedish mutant assessed as soluble amyloid beta (1 to 42) level per mg of protein in brain at 50 mg/kg/day, po for 3 months by ELISA (Rvb = 17.34 +/- 5.17 ng per mg of protein)	Mus musculus	1	ALA2176979	organism-based format	Scientific Literature
6.	ALA2185362	F	Antialzheimer activity in transgenic mouse expressing PS1/APP swedish mutant assessed as insoluble amyloid beta (1 to 40) level per mg of protein in brain at 50 mg/kg/day, po for 3 months by ELISA (Rvb = 137.38+/- 58.13 ng per mg of protein)	Mus musculus	1	ALA2176979	organism-based format	Scientific Literature
7.	ALA2185363	F	Antialzheimer activity in transgenic mouse expressing PS1/APP swedish mutant assessed as soluble amyloid beta (1 to 40) level per mg of protein in brain at 50 mg/kg/day, po for 3 months by ELISA (Rvb = 8.66 +/- 1.81 ng per mg of protein)	Mus musculus	1	ALA2176979	organism-based format	Scientific Literature
8.	ALA2185364	F	Inhibition of RAGE-mediated influx of human amyloid beta (1 to 42) into ICR mouse brain at 25 mg/kg, ip administered 20 mins prior to human amyloid beta (1 to 40)-injection measured after 30 mins by ELISA relative to control	Mus musculus	3	ALA2176979	organism-based format	Scientific Literature
9.	ALA2185365	A	Cytotoxicity against rat C6 cells at 0.1 to 10 uM after 18 hrs	Rattus norvegicus	3	ALA2176979	cell-based format	Scientific Literature
10.	ALA2185366	B	Inhibition of receptor for advanced glycation end product binding to amyloid beta 42 in rat C6 cells assessed as NFkappaB activation at 0.1 to 10 uM after 18 hrs by reporter gene assay	Rattus norvegicus	3	ALA2176979	cell-based format	Scientific Literature
11.	ALA2185367	B	Inhibition of human recombinant biotinylated receptor for advanced glycation end product expressed in Escherichia coli DE3 assessed as inhibition of binding to amyloid beta (1 to 42) after 60 mins by TMB-ELISA	Homo sapiens	2	ALA2176979	assay format	Scientific Literature
12.	ALA2185368	B	Inhibition of human recombinant biotinylated receptor for advanced glycation end product expressed in Escherichia coli DE3 assessed as inhibition of binding to amyloid beta (1 to 42) at 20 uM after 60 mins by TMB-ELISA	Homo sapiens	39	ALA2176979	assay format	Scientific Literature
13.	ALA2185369	F	Reduction in human amyloid beta (1 to 42) level in ICR mouse plasma at 25 mg/kg, ip administered 20 mins prior to human amyloid beta (1 to 40)-injection measured after 30 mins by ELISA relative to control	Mus musculus	3	ALA2176979	organism-based format	Scientific Literature
14.	ALA3243670	A	AUC in Sprague-Dawley rat at 2 mg/kg, iv	Rattus norvegicus	2	ALA3232933	organism-based format	Scientific Literature
15.	ALA4030325	B	Inhibition of amyloid beta binding to biotin-labeled human RAGE domain V after 60 mins by ELISA	Homo sapiens	2	ALA4028844	single protein format	Scientific Literature
16.	ALA4030326	A	Cytotoxicity against mouse HT22 cells assessed as cell survival at 10 uM after 18 hrs by MTT assay relative to control	Mus musculus	3	ALA4028844	cell-based format	Scientific Literature
17.	ALA5165149	B	Inhibition of biotinylated human RAGE/amyloid beta interaction incubated for 120 mins by ELISA assay	Homo sapiens	37	ALA5154874	single protein format	Scientific Literature