# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2185809 | B | Binding affinity to MDR assessed as efflux ratio of permeability from basal to apical to apical to basal side | 13 | assay format | Scientific Literature | |||
2. | ALA2185810 | A | Intrinsic clearance in human liver microsomes at 0.1 uM by LC-MS/MS analysis | Homo sapiens | 15 | microsome format | Scientific Literature | ||
3. | ALA2185811 | B | Selectivity ratio of IC50 for human recombinant PDE1C to IC50 for human recombinant PDE9A | Homo sapiens | 2 | assay format | Scientific Literature | ||
4. | ALA2185812 | B | Inhibition of human recombinant PDE1C expressed in Sf9 cells using [3H]cAMP as substrate after 30 mins by scintillation proximity assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
5. | ALA2185813 | B | Inhibition of human recombinant PDE9A expressed in Sf9 cells using [3H]cGMP as substrate after 30 mins by scintillation proximity assay | Homo sapiens | 15 | cell-based format | Scientific Literature |