| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2185809 | B | Binding affinity to MDR assessed as efflux ratio of permeability from basal to apical to apical to basal side | 13 | assay format | Scientific Literature | |||
| 2. | ALA2185810 | A | Intrinsic clearance in human liver microsomes at 0.1 uM by LC-MS/MS analysis | Homo sapiens | 15 | microsome format | Scientific Literature | ||
| 3. | ALA2185812 | B | Inhibition of human recombinant PDE1C expressed in Sf9 cells using [3H]cAMP as substrate after 30 mins by scintillation proximity assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 4. | ALA2185813 | B | Inhibition of human recombinant PDE9A expressed in Sf9 cells using [3H]cGMP as substrate after 30 mins by scintillation proximity assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 5. | ALA4259315 | A | Efflux ratio of permeability across basolateral to apical over apical to basolateral side in MDCK cells expressing MDR1 at 0.5 uM after 60 mins by LC-MS/MS analysis | Canis lupus familiaris | 16 | cell-based format | Scientific Literature | ||
| 6. | ALA4259316 | P | Acidic dissociation constant, pKa of compound at 10 uM by UV/Vis spectroscopy | 12 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA4259317 | P | Basic dissociation constant, pKa of compound at 10 uM by UV/Vis spectroscopy | 16 | small-molecule physicochemical format | Scientific Literature | |||
| 8. | ALA4259318 | B | Inhibition of PDE9 (unknown origin) using [3H]-cGMP as substrate after 1 hr by scintillation counting method | Homo sapiens | 13 | single protein format | Scientific Literature |
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