| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2185583 | B | Inhibition of Bacillus anthracis PA U7 mutant assessed as reduction in SDS-resistant oligomer level in CHO C4 cells at 100 uM after 1 hr by Western blot analysis relative to untreated-control in presence of lethal factor | Bacillus anthracis | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA2185584 | B | Inhibition of Bacillus anthracis Protective antigen assessed as reduction in SDS-resistant oligomer level in CHO C4 cells at 100 uM after 1 hr by Western blot analysis relative to untreated-control in presence of lethal factor | Bacillus anthracis | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA2185585 | B | Inhibition of Bacillus anthracis PA U7 mutant assessed as reduction in PA83 level in CHO C4 cells at 100 uM after 1 hr by Western blot analysis relative to untreated-control in presence of lethal factor | Bacillus anthracis | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA2185586 | B | Inhibition of Bacillus anthracis Protective antigen assessed as reduction in PA83 level in CHO C4 cells at 100 uM after 1 hr by Western blot analysis relative to untreated-control in presence of lethal factor | Bacillus anthracis | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA2185589 | A | Cytotoxicity against human HT1080 cells compound incubated at 10 to 100 uM for extended period by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2185590 | A | Cytotoxicity against mouse RAW264.7 cells compound incubated at 10 to 100 uM for extended period by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA2185591 | B | Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in RAW264.7 cells at 3 uM compound co-treated for 5 hrs with antigen measured after 48 hrs by MTT assay in presence of FP59 | Bacillus anthracis | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA2185596 | B | Inhibition of human furin-mediated TGFalpha-PE38 cleavage at 1 to 100 uM after 1 hr by Western blot analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 9. | ALA2185597 | B | Inhibition of human furin-mediated Bacillus anthracis PA83 cleavage at 1 to 100 uM after 1 hr by Western blot analysis | Bacillus anthracis | 3 | single protein format | Scientific Literature | ||
| 10. | ALA2185598 | B | Inhibition of Bacillus anthracis Protective antigen assessed as reduction in SDS-resistant oligomer level in CHO C4 cells at 100 uM after 1 hr by Western blot analysis relative to untreated-control | Bacillus anthracis | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA2185599 | B | Inhibition of Bacillus anthracis Protective antigen assessed as reduction in PA63 level in CHO C4 cells at 100 uM after 1 hr by Western blot analysis relative to untreated-control | Bacillus anthracis | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA2185600 | B | Inhibition of Bacillus anthracis Protective antigen assessed as reduction in PA83 level in CHO C4 cells at 100 uM after 1 hr by Western blot analysis relative to untreated-control | Bacillus anthracis | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA2185601 | B | Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in RAW264.7 cells by MTT assay in presence of fetal bovine serum | Bacillus anthracis | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA2185602 | B | Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in RAW264.7 cells at 10 uM compound co-treated for 5 hrs with antigen by MTT assay in presence of lethal factor | Bacillus anthracis | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA2185603 | B | Inhibition of matrix metalloprotease activated Bacillus anthracis Protective antigen-mediated cytotoxicity in HT1080 cells compound co-treated for 5 hrs with antigen measured after 48 hrs by MTT assay in presence of FP59 | Bacillus anthracis | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA2187863 | B | Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in HT1080 cells compound co-treated for 5 hrs with antigen measured after 48 hrs by MTT assay in presence of FP59 | Bacillus anthracis | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA2187864 | B | Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in RAW264.7 cells compound co-treated for 5 hrs with antigen measured after 48 hrs by MTT assay in presence of FP59 | Bacillus anthracis | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA2187865 | B | Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in RAW264.7 cells compound co-treated for 5 hrs with antigen by MTT assay in presence of lethal factor | Bacillus anthracis | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA2187866 | B | Inhibition of LF-induced Bacillus anthracis PA83 N645C mutant oligomerization expressed in Escherichia coli BL-21 cells at 100 uM over 40 mins by FRET assay | Bacillus anthracis | 4 | cell-based format | Scientific Literature | ||
| 20. | ALA2187867 | B | Inhibition of Bacillus anthracis Protective antigen-mediated cytotoxicity in human HT1080 cells by MTT assay in presence of fetal bovine serum | Bacillus anthracis | 3 | cell-based format | Scientific Literature |
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