# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2183806 | F | Antiapicomplexan activity against Toxoplasma gondii RH tachyzoites infected in HFF cells assessed as [3H]-uracil incorporation after 24 hrs by scintillation luminescence counter | Toxoplasma gondii | 39 | organism-based format | Scientific Literature | ||
2. | ALA2354177 | B | Inhibition of Wnt3A/beta-casein signaling in HEK293 cells after 8 hrs by TOPflash reporter assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
3. | ALA2354178 | B | Induction of internalization of Frizzled1-GFP (unknown origin) expressed in human U2OS cells at 12.5 uM after 6 hrs by confocal microscopy | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
4. | ALA2354221 | F | PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT. (Class of assay: confirmatory) | 172,532 | assay format | PubChem BioAssays | |||
5. | ALA4704510 | F | Antiviral activity against GFP-fused Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of plaque formation incubated for 7 days by GFP reporter gene assay | Human adenovirus 5 | 68 | organism-based format | Scientific Literature | ||
6. | ALA4704511 | A | Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by alamarBlue assay | Homo sapiens | 68 | cell-based format | Scientific Literature | ||
7. | ALA4704512 | T | Selectivity index, ratio of CC50 for cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by alamarBlue assay to IC50 for antiviral activity against Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of plaque formation incubated for 7 days by GFP reporter gene assay | 68 | cell-based format | Scientific Literature | |||
8. | ALA4704513 | F | Antiviral activity against Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of plaque formation at 10 uM incubated for 7 days by GFP reporter gene assay relative to control | Human adenovirus 5 | 66 | organism-based format | Scientific Literature | ||
9. | ALA4821031 | B | Inhibition of NS-1in Zika virus | Zika virus | 69 | assay format | Scientific Literature | ||
10. | ALA4821032 | B | Inhibition of envelope protein in Zika virus | Zika virus | 69 | assay format | Scientific Literature | ||
11. | ALA4821033 | A | Metabolic stability in rat liver microsomes | Rattus norvegicus | 69 | microsome format | Scientific Literature | ||
12. | ALA4821034 | A | Permeability of compound by PAMPA assay | 69 | assay format | Scientific Literature | |||
13. | ALA4821035 | P | Solubility of the compound | 69 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA4822329 | F | Antiviral activity against RSV infected in human A549 cells assessed as reduction in viral titer at 10 uM incubated for 15 hrs by immunostaining analysis | Respiratory syncytial virus | 21 | organism-based format | Scientific Literature | ||
15. | ALA4822330 | A | Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 15 hrs by LDH assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
16. | ALA5135650 | F | Antimicrobial activity against clinical isolate CF333-2007 Pseudomonas aeruginosa DK2 measured after 18 hrs in presence of polymyxin B by microbroth dilution assay | Pseudomonas aeruginosa | 30 | organism-based format | Scientific Literature | ||
17. | ALA5135651 | F | Antimicrobial activity against clinical isolate CF333-2007 Pseudomonas aeruginosa DK2 assessed as polymyxin B MIC measured after 18 hrs by microbroth dilution assay | Pseudomonas aeruginosa | 30 | organism-based format | Scientific Literature | ||
18. | ALA5135652 | F | Synergistic antibacterial activity against clinical isolate CF333-2007 Pseudomonas aeruginosa DK2 assessed as fractional inhibitory concentration index incubated for 18 hrs in presence of Polymyxin B | Pseudomonas aeruginosa | 21 | organism-based format | Scientific Literature | ||
19. | ALA5135666 | F | Antimicrobial activity against clinical isolate CF333-2007 Pseudomonas aeruginosa DK2 measured after 18 hrs by microbroth dilution assay | Pseudomonas aeruginosa | 30 | organism-based format | Scientific Literature |