# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2188860 | F | Reduction in morphine dependence in nonwithdrawn rhesus monkey model assessed as attenuation of naloxone-induced naloxone-precipitated withdrawal effect at 2 mg/kg | Macaca mulatta | 1 | organism-based format | Scientific Literature | ||
2. | ALA2188861 | F | Reduction in morphine dependence in withdrawn rhesus monkey model assessed as attenuation of withdrawal effects at 0.5 mg/kg | Macaca mulatta | 1 | organism-based format | Scientific Literature | ||
3. | ALA2188862 | F | Reduction in morphine dependence in withdrawn rhesus monkey model assessed as attenuation of withdrawal effects at 0.1 mg/kg | Macaca mulatta | 1 | organism-based format | Scientific Literature | ||
4. | ALA2188863 | F | Inhibition of bremazocine-induced antinociception in mouse assessed as reversal of inhibition of acetic acid-induced writhing at 32 mg/kg administered 24 hrs post bremazocine treatment | Mus musculus | 4 | organism-based format | Scientific Literature | ||
5. | ALA2188864 | F | Inhibition of BW373U86-induced antinociception in mouse assessed as reversal of inhibition of acetic acid-induced writhing at 32 mg/kg administered 24 hrs post BW373U86 treatment | Mus musculus | 4 | organism-based format | Scientific Literature | ||
6. | ALA2188865 | F | Inhibition of morphine-induced antinociception in mouse assessed as reversal of inhibition of acetic acid-induced writhing at 32 mg/kg administered 24 hrs post morphine treatment | Mus musculus | 4 | organism-based format | Scientific Literature | ||
7. | ALA2188870 | F | Inhibition of morphine-induced antinociception in mouse assessed as tail withdrawal latency at 100 mg/kg administered 24 hrs post morphine treatment measured up to 9 days by 55 degC warm water test relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA2188871 | F | Inhibition of morphine-induced antinociception in mouse assessed as tail withdrawal latency at 10 mg/kg administered 24 hrs post morphine treatment measured after 24 hrs by 55 degC warm water test relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
9. | ALA2188872 | F | Inhibition of morphine-induced antinociception in mouse assessed as tail withdrawal latency at 10 mg/kg administered 24 hrs post morphine treatment measured after 30 mins by 55 degC warm water test relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
10. | ALA2182247 | F | Inhibition of morphine-induced antinociception in mouse assessed as tail withdrawal latency at 100 mg/kg administered 24 hrs post morphine treatment by 55 degC warm water test relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
11. | ALA2182248 | F | Antinociceptive activity in mouse assessed as inhibition of acetic acid-induced writhing at 10 mg/kg | Mus musculus | 1 | organism-based format | Scientific Literature | ||
12. | ALA2182249 | F | Inhibition of morphine-induced antinociception in mouse assessed as rightward shift of morphine curve at 10 mg/kg administered 24 hrs post morphine treatment by 55 degC warm water test relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
13. | ALA2183120 | F | Antinociceptive activity in mouse assessed as tail withdrawal latency at 100 mg/kg by 55 degC warm water test | Mus musculus | 6 | organism-based format | Scientific Literature | ||
14. | ALA2183121 | F | Antinociceptive activity in mouse assessed as tail withdrawal latency at 100 mg/kg by 50 degC warm water test | Mus musculus | 5 | organism-based format | Scientific Literature | ||
15. | ALA2183131 | F | Partial agonist activity at MOR in guinea pig ileum assessed as inhibition of electrically-stimulated twitch in presence of CTAP | Cavia porcellus | 3 | tissue-based format | Scientific Literature | ||
16. | ALA2183133 | F | Partial agonist activity at MOR in guinea pig ileum assessed as inhibition of electrically-stimulated twitch | Cavia porcellus | 2 | tissue-based format | Scientific Literature | ||
17. | ALA2183134 | B | Displacement of [3H]U69593 from KOR in guinea pig brain membrane | Cavia porcellus | 9 | cell membrane format | Scientific Literature | ||
18. | ALA2183135 | B | Displacement of [3H]Cl-DPDPE from DOR in guinea pig brain membrane | Cavia porcellus | 9 | cell membrane format | Scientific Literature | ||
19. | ALA2183136 | B | Displacement of [3H]DAMGO from MOR in guinea pig brain membrane | Cavia porcellus | 9 | cell membrane format | Scientific Literature |