# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2188801 | T | Toxicity in Staphylococcus aureus infected mouse thigh infection model assessed as incidence of adverse events | Mus musculus | 1 | organism-based format | Scientific Literature | ||
2. | ALA2188802 | A | Toxicity against Candida albicans | Candida albicans | 6 | organism-based format | Scientific Literature | ||
3. | ALA2188803 | F | Antimicrobial activity against Staphylococcus aureus infected in mouse thigh infection model assessed as compound dose causing microbial infection stasis administered as single dose | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
4. | ALA2188804 | T | Toxicity against human A549 cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
5. | ALA2188805 | F | Antimicrobial activity against vancomycin-resistant Enterococcus faecalis by broth microdilution method | Enterococcus faecalis | 2 | organism-based format | Scientific Literature | ||
6. | ALA2188806 | F | Antimicrobial activity against linezolid-resistant Enterococcus faecium by broth microdilution method | Enterococcus faecium | 2 | organism-based format | Scientific Literature | ||
7. | ALA2188807 | F | Antimicrobial activity against Staphylococcus epidermidis by broth microdilution method | Staphylococcus epidermidis | 2 | organism-based format | Scientific Literature | ||
8. | ALA2188808 | F | Antimicrobial activity against Streptococcus pyogenes by broth microdilution method | Streptococcus pyogenes | 2 | organism-based format | Scientific Literature | ||
9. | ALA2188809 | F | Antimicrobial activity against methicillin and quinolone-resistant Staphylococcus aureus by broth microdilution method | Staphylococcus aureus | 23 | organism-based format | Scientific Literature | ||
10. | ALA2188810 | B | Inhibition of human thymidylate kinase assessed as effect on ATP production by Escherichia coli DdlA and Malachite green reagent based assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
11. | ALA2188811 | F | Antimicrobial activity against methicillin and quinolone-sensitive Staphylococcus aureus by broth microdilution method | Staphylococcus aureus | 23 | organism-based format | Scientific Literature | ||
12. | ALA2188812 | F | Antimicrobial activity against Streptococcus pneumoniae by broth microdilution method | Streptococcus pneumoniae | 23 | organism-based format | Scientific Literature | ||
13. | ALA2188813 | P | Partition coefficient, log D of the compound at pH 7.4 by shake flask method | 23 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA2188814 | B | Inhibition of Staphylococcus aureus thymidylate kinase assessed as effect on conversion of dTDP to dTMP by luciferin/luciferase reporter gene based assay | Staphylococcus aureus | 40 | assay format | Scientific Literature | ||
15. | ALA2188815 | B | Inhibition of Streptococcus pneumoniae thymidylate kinase assessed as effect on conversion of dTDP to dTMP by luciferin/luciferase reporter gene based assay | Streptococcus pneumoniae | 40 | assay format | Scientific Literature | ||
16. | ALA3300177 | B | Inhibition of Staphylococcus aureus TMK assessed as decrease in ATP production using dTDP and ADP as substrate after 3.5 hrs by luciferin/luciferase based luminescence analysis | Staphylococcus aureus | 29 | assay format | Scientific Literature | ||
17. | ALA3300179 | F | Antibacterial activity against Staphylococcus aureus ARC 516 assessed as growth inhibition by broth microdilution method | Staphylococcus aureus | 18 | organism-based format | Scientific Literature | ||
18. | ALA3300180 | F | Antibacterial activity against methicillin-resistant and quinolone-resistant Staphylococcus aureus ARC 517 assessed as growth inhibition by broth microdilution method | Staphylococcus aureus | 18 | organism-based format | Scientific Literature | ||
19. | ALA3300182 | A | Fraction unbound in human plasma at 10 uM after 5 hrs by rapid equilibrium dialysis method | Homo sapiens | 11 | cell-free format | Scientific Literature | ||
20. | ALA3300183 | A | Fraction unbound in mouse plasma at 10 uM after 5 hrs by rapid equilibrium dialysis method | Mus musculus | 11 | cell-free format | Scientific Literature |