| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2187683 | F | Cell cycle arrest in human LNCAP cells assessed as decrease in accumulation at S phase after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
| 2. | ALA2187684 | F | Cell cycle arrest in human LNCAP cells assessed as decrease in accumulation at G0/G1 phase after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
| 3. | ALA2187685 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at sub G1 phase at 200 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 0.3 +/- 0.2 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
| 4. | ALA2187686 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at sub G1 phase at 100 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 0.3 +/- 0.2 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
| 5. | ALA2187687 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at G2/M phase at 200 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 10.1 +/- 1.4 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
| 6. | ALA2187688 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at G2/M phase at 100 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 10.1 +/- 1.4 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
| 7. | ALA2187689 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at S phase at 200 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 15.6 +/- 1.3 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
| 8. | ALA2187690 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at S phase at 100 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 15.6 +/- 1.3 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
| 9. | ALA2187691 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at G0/G1 phase at 200 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 74.3 +/- 0.1 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
| 10. | ALA2187692 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at G0/G1 phase at 100 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 74.3 +/- 0.1 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
| 11. | ALA2187693 | F | Cytotoxicity against human LNCAP cells assessed as growth inhibition after 72 hrs by MTT assay | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
| 12. | ALA2187695 | B | Competitive inhibition of human recombinant furin expressed in Drosophila S2 cells using pyroGlu-Arg-Val-Lys-Arg-methyl-coumaryl-7-amide as substrate at pH 7.5 after 60 mins by spectrofluorometric analysis | Homo sapiens | 17 | ALA2176991 | cell-based format | Scientific Literature | |
| 13. | ALA2187696 | F | Cytotoxicity against human DU145 cells assessed as growth inhibition after 72 hrs by MTT assay | Homo sapiens | 4 | ALA2176991 | cell-based format | Scientific Literature | |
| 14. | ALA2187697 | F | Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay | Homo sapiens | 1 | ALA2176991 | cell-based format | Scientific Literature | |
| 15. | ALA2187698 | B | Selectivity ratio of Ki for human recombinant furin to Ki for human recombinant PACE4 | Homo sapiens | 14 | ALA2176991 | assay format | Scientific Literature | |
| 16. | ALA2187699 | B | Competitive inhibition of human recombinant PACE4 expressed in Drosophila S2 cells using pyroGlu-Arg-Val-Lys-Arg-methyl-coumaryl-7-amide as substrate at pH 6.5 after 60 mins by spectrofluorometric analysis | Homo sapiens | 17 | ALA2176991 | cell-based format | Scientific Literature | |
| 17. | ALA3117741 | A | Cellular uptake in human DU145 cells after 1 hr by propidium iodide staining-based FACS analysis | Homo sapiens | 3 | ALA3112425 | cell-based format | Scientific Literature | |
| 18. | ALA3117742 | T | Acute toxicity in human DU145 cells assessed as cell death/lysis at 100 uM after 4 hrs by LDH assay | Homo sapiens | 12 | ALA3112425 | cell-based format | Scientific Literature | |
| 19. | ALA3117743 | F | Cytotoxicity against human PC3 cells up to 350 uM after 72 hrs by MTT assay | Homo sapiens | 8 | ALA3112425 | cell-based format | Scientific Literature | |
| 20. | ALA3117746 | F | Cytotoxicity against human LNCAP cells after 72 hrs by MTT assay | Homo sapiens | 10 | ALA3112425 | cell-based format | Scientific Literature |
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