| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2187381 | F | Agonist activity against CXCR5 expressed in U87.CD.CXCR5 cells assessed as stimulation of calcium signaling incubated for 10 mins by FLIPR | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 2. | ALA2187382 | F | Agonist activity against CXCR4 expressed in U87.CD.CXCR4 cells assessed as stimulation of calcium signaling incubated for 10 mins by FLIPR | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA2187383 | B | Inhibition of anti-CXCR4 mAbs clone 1D9 binding to CXCR4 in human SUPT1 cells incubated for 15 mins by FACS | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 4. | ALA2187384 | B | Inhibition of anti-CXCR4 mAbs clone 12G5 binding to CXCR4 in human SUPT1 cells incubated for 15 mins by FACS | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 5. | ALA2187385 | B | Inhibition of anti-CXCR4 mAbs clone 173 binding to CXCR4 in human SUPT1 cells incubated for 15 mins by FACS | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 6. | ALA2187757 | F | Antagonist activity against CXCR5 expressed in U87.CD.CXCR5 cells assessed as inhibition of CCL3L1-induced calcium signaling incubated for 10 mins by FLIPR | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 7. | ALA2187758 | A | Cytotoxicity against human PBMC cells by MTT assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 8. | ALA2187759 | F | Antiviral activity against X4 HIV1 NL4.3 infected in human PBMC assessed as inhibition of viral replication pre-incubated for 30 mins measured 5 days post infection by MTT assay | Human immunodeficiency virus 1 | 9 | organism-based format | Scientific Literature | ||
| 9. | ALA2187760 | A | Cytotoxicity against human MT4 cells by MTT assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 10. | ALA2187761 | F | Antiviral activity against X4 HIV1 NL4.3 infected in human MT4 cells assessed as inhibition of viral replication pre-incubated for 30 mins measured 5 days post infection by MTT assay | Human immunodeficiency virus 1 | 9 | organism-based format | Scientific Literature | ||
| 11. | ALA2187762 | F | Antagonist activity against CXCR4 expressed in U87.CD.CXCR4 cells assessed as inhibition of CXCL12-induced calcium signaling incubated for 10 mins by FLIPR | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 12. | ALA2187763 | B | Inhibition of CXCL-12'AF647 binding to CXCR4 in human SUPT1 cells incubated for 15 mins by FACS | Homo sapiens | 10 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!