# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2187682 | A | Stability of the compound in presence of aminopeptidase | 1 | ALA2176991 | assay format | Scientific Literature | ||
2. | ALA2187683 | F | Cell cycle arrest in human LNCAP cells assessed as decrease in accumulation at S phase after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
3. | ALA2187684 | F | Cell cycle arrest in human LNCAP cells assessed as decrease in accumulation at G0/G1 phase after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
4. | ALA2187685 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at sub G1 phase at 200 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 0.3 +/- 0.2 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
5. | ALA2187686 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at sub G1 phase at 100 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 0.3 +/- 0.2 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
6. | ALA2187687 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at G2/M phase at 200 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 10.1 +/- 1.4 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
7. | ALA2187688 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at G2/M phase at 100 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 10.1 +/- 1.4 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
8. | ALA2187689 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at S phase at 200 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 15.6 +/- 1.3 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
9. | ALA2187690 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at S phase at 100 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 15.6 +/- 1.3 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
10. | ALA2187691 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at G0/G1 phase at 200 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 74.3 +/- 0.1 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
11. | ALA2187692 | F | Cell cycle arrest in human LNCAP cells assessed as accumulation at G0/G1 phase at 100 uM after 96 hrs by propidium iodide staining-based FACS flow cytometric analysis (Rvb = 74.3 +/- 0.1 %) | Homo sapiens | 2 | ALA2176991 | cell-based format | Scientific Literature | |
12. | ALA3117741 | A | Cellular uptake in human DU145 cells after 1 hr by propidium iodide staining-based FACS analysis | Homo sapiens | 3 | ALA3112425 | cell-based format | Scientific Literature | |
13. | ALA3117742 | T | Acute toxicity in human DU145 cells assessed as cell death/lysis at 100 uM after 4 hrs by LDH assay | Homo sapiens | 12 | ALA3112425 | cell-based format | Scientific Literature | |
14. | ALA3117744 | F | Cytotoxicity against human PC3 cells after 72 hrs by MTT assay | Homo sapiens | 4 | ALA3112425 | cell-based format | Scientific Literature | |
15. | ALA3117746 | F | Cytotoxicity against human LNCAP cells after 72 hrs by MTT assay | Homo sapiens | 10 | ALA3112425 | cell-based format | Scientific Literature | |
16. | ALA3117748 | F | Cytotoxicity against human DU145 cells after 72 hrs by MTT assay | Homo sapiens | 11 | ALA3112425 | cell-based format | Scientific Literature | |
17. | ALA3117749 | A | Half life in CD-1 mouse plasma at 0.5 ug/uL by RP-HPLC analysis | Mus musculus | 6 | ALA3112425 | cell-free format | Scientific Literature | |
18. | ALA3117752 | B | Selectivity ratio of Ki for human recombinant furin to Ki for human recombinant PACE4 | Homo sapiens | 3 | ALA3112425 | assay format | Scientific Literature | |
19. | ALA3117753 | B | Inhibition of human recombinant furin expressed in drosophila schneider 2 cells using pyroGlu-Arg-Thr-Lys-Arg-AMC as substrate after 1 hr | Homo sapiens | 21 | ALA3112425 | cell-based format | Scientific Literature | |
20. | ALA3117754 | B | Inhibition of human recombinant PACE4 expressed in drosophila schneider 2 cells using pyroGlu-Arg-Thr-Lys-Arg-AMC as substrate after 1 hr | Homo sapiens | 21 | ALA3112425 | cell-based format | Scientific Literature |