# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2187825 | Functional | Up-regulation of cathepsin-D level in lysosome of rat hippocampal slice cultures at 3 to 10 uM after 4 days by immunoblot analysis in presence of brefeldin-A | Rattus norvegicus | 1 | ALA2176904 | tissue-based format | Scientific Literature | |
2. | ALA2187826 | Functional | Up-regulation of cathepsin-B level in lysosome of rat hippocampal slice cultures at 3 to 10 uM after 4 days by immunoblot analysis in presence of brefeldin-A | Rattus norvegicus | 1 | ALA2176904 | tissue-based format | Scientific Literature | |
3. | ALA2187827 | Functional | Up-regulation of cathepsin-D level in lysosome of rat hippocampal slice cultures at 3 to 10 uM after 4 days by immunoblot analysis | Rattus norvegicus | 1 | ALA2176904 | tissue-based format | Scientific Literature | |
4. | ALA2188219 | Functional | Up-regulation of cathepsin-B level in lysosome of rat hippocampal slice cultures at 3 to 10 uM after 4 days by immunoblot analysis | Rattus norvegicus | 1 | ALA2176904 | tissue-based format | Scientific Literature | |
5. | ALA2188220 | Binding | Inhibition of cathepsin-B using Z-Arg-Arg AMC as substrate by fluorescence assay relative to control | 4 | ALA2176904 | single protein format | Scientific Literature | ||
6. | ALA2188221 | Binding | Inhibition of cathepsin-B using Z-Arg-Arg AMC as substrate by fluorescence assay | 4 | ALA2176904 | single protein format | Scientific Literature | ||
7. | ALA2406853 | Binding | Inhibition of Trypanosoma brucei rhodesain assessed as second order rate constant | Trypanosoma brucei | 10 | ALA2401704 | assay format | Scientific Literature | |
8. | ALA2406871 | Functional | Antitrypanosomal activity against blood stream form of Trypanosoma brucei brucei | Trypanosoma brucei brucei | 15 | ALA2401704 | organism-based format | Scientific Literature |