| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2187440 | B | Binding affinity at human recombinant ARTD8 expressed in Escherichia coli BL21 (DE3) R3 pRARE cells assessed as thermal stability shift by differential scanning fluorimetry | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 2. | ALA2187441 | B | Binding affinity at human recombinant ARTD7 expressed in Escherichia coli BL21 (DE3) R3 pRARE cells assessed as thermal stability shift by differential scanning fluorimetry | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 3. | ALA3411252 | B | Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity at 100 uM after 24 hrs by CACCC-responsive promoter driven TK-luciferase reporter gene assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 4. | ALA3411253 | B | Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter driven TK-luciferase reporter gene assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 5. | ALA3411255 | B | Inhibition of KLF10 (unknown origin) binding to DNA at 8 uM incubated for 4 hrs followed by biotin-labeled probes addition and incubated for another 1 hr by electromobility gel shift assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA3411256 | B | Inhibition of KLF10 (unknown origin) binding to DNA at 50 uM incubated for 4 hrs followed by biotin-labeled probes addition and incubated for another 1 hr by electromobility gel shift assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA3411259 | F | Inhibition of mouse T regulatory cell differentiation assessed as inhibition of TGFbeta1-induced conversion of CD4(+) and CD25(-) cells to CD4(+) and CD25(+) cells incubated for 3 days by flow cytometry | Mus musculus | 3 | assay format | Scientific Literature | ||
| 8. | ALA3411260 | F | Inhibition of Foxp3 gene expression in mouse T regulatory cells at 50 uM measured during TGFbeta1-induced conversion of CD4(+) and CD25(-) cells to CD4(+) and CD25(+) cells incubated for 3 days by real-time quantitative PCR method | Mus musculus | 3 | cell-based format | Scientific Literature |
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