# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2184465 | F | Antagonist activity at human P2X7 receptor by cell-based calcium influx assay | Homo sapiens | 8 | ALA2177033 | cell-based format | Scientific Literature | |
2. | ALA2184466 | F | Antagonist activity at human P2X3 receptor by cell-based calcium influx assay | Homo sapiens | 8 | ALA2177033 | cell-based format | Scientific Literature | |
3. | ALA2184467 | F | Antagonist activity at human P2X2 receptor by cell-based calcium influx assay | Homo sapiens | 8 | ALA2177033 | cell-based format | Scientific Literature | |
4. | ALA2184468 | F | Antagonist activity at human P2X1 receptor by cell-based calcium influx assay | Homo sapiens | 8 | ALA2177033 | cell-based format | Scientific Literature | |
5. | ALA2184469 | F | Antagonist activity at mouse P2X4 receptor by cell-based calcium influx assay | Mus musculus | 10 | ALA2177033 | cell-based format | Scientific Literature | |
6. | ALA2184470 | F | Antagonist activity at rat P2X4 receptor by cell-based calcium influx assay | Rattus norvegicus | 11 | ALA2177033 | cell-based format | Scientific Literature | |
7. | ALA2184474 | B | Competitive antagonist activity at human P2X4 receptor expressed in 1321N1 cell membrane assessed as inhibition of [35S]ATPgammaS binding at >10 uM by scintillation counting | Homo sapiens | 2 | ALA2177033 | cell-based format | Scientific Literature | |
8. | ALA2184476 | B | Negative allosteric modulation at human P2X4 receptor expressed in 1321N1 cell membrane assessed as inhibition of [35S]ATPgammaS binding by scintillation counting | Homo sapiens | 7 | ALA2177033 | cell-based format | Scientific Literature | |
9. | ALA2184477 | F | Antagonist activity at human P2X4 receptor expressed in 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubated at 100 uM for 30 mins before ATP treatment by Fluo-4 AM fluorescence method | Homo sapiens | 27 | ALA2177033 | cell-based format | Scientific Literature | |
10. | ALA2184479 | F | Antagonist activity at human P2X4 receptor expressed in 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx compound preincubated for 30 mins before ATP treatment by Fluo-4 AM fluorescence method | Homo sapiens | 58 | ALA2177033 | cell-based format | Scientific Literature | |
11. | ALA2184481 | F | Antagonist activity at human P2X7 receptor at 10 uM by cell-based calcium influx assay | Homo sapiens | 6 | ALA2177033 | cell-based format | Scientific Literature | |
12. | ALA2184482 | F | Antagonist activity at human P2X3 receptor at 10 uM by cell-based calcium influx assay | Homo sapiens | 6 | ALA2177033 | cell-based format | Scientific Literature | |
13. | ALA2184483 | F | Antagonist activity at human P2X2 receptor at 10 uM by cell-based calcium influx assay | Homo sapiens | 7 | ALA2177033 | cell-based format | Scientific Literature | |
14. | ALA2184484 | F | Antagonist activity at human P2X1 receptor at 10 uM by cell-based calcium influx assay | Homo sapiens | 4 | ALA2177033 | cell-based format | Scientific Literature | |
15. | ALA2184486 | F | Antagonist activity at mouse P2X4 receptor at 10 uM by cell-based calcium influx assay | Mus musculus | 2 | ALA2177033 | cell-based format | Scientific Literature |