| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2187446 | F | Antipsychotic activity in iv dosed NMRI mouse assessed as inhibition of SCH-23390-induced hypolocomotion administered 30 mins prior to SCH-23390 challenge measured up to 30 mins | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 2. | ALA2187448 | B | Selectivity ratio of IC50 for PDE1B1 to IC50 for rat recombinant PDE10A2 | 3 | assay format | Scientific Literature | |||
| 3. | ALA2187449 | B | Inhibition of rat recombinant PDE10A2 expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 60 mins by scintillation proximity assay | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA2182995 | F | Antipsychotic activity in iv dosed rat assessed as inhibition of apomorphine-induced Stereotypy administered 1 hr prior to apomorphine challenge | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 5. | ALA2182996 | F | Antipsychotic activity in sc dosed Wiga rat assessed as inhibition of phencyclidine-induced hyperlocomotion administered 60 mins prior to phencyclidine challenge measured up to 30 mins | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 6. | ALA2182997 | F | Antipsychotic activity in sc dosed Wistar Wiga rat assessed as latency to avoid an electric shock measured up to 120 mins by conditioned avoidance responce test | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 7. | ALA4650107 | B | Thermal Shift Assay. Domain start/stop: M626-G740 | Homo sapiens | 1,014 | single protein format | EUbOPEN Chemogenomic Library | ||
| 8. | ALA4725212 | T | Incucyte cell viability with HEK293T | Homo sapiens | 1,713 | cell-based format | EUbOPEN Chemogenomic Library | ||
| 9. | ALA4725213 | T | Incucyte cell viability with human fibroblast | Homo sapiens | 1,718 | cell-based format | EUbOPEN Chemogenomic Library | ||
| 10. | ALA4725214 | T | Incucyte cell viability with U2OS | Homo sapiens | 1,712 | cell-based format | EUbOPEN Chemogenomic Library | ||
| 11. | ALA4880023 | B | GPCRScan assay: inhibition of 5-HT1A | Homo sapiens | 180 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 12. | ALA4880024 | B | GPCRScan assay: inhibition of 5-HT1B | Homo sapiens | 181 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 13. | ALA4880025 | B | GPCRScan assay: inhibition of 5-HT1D | Homo sapiens | 181 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 14. | ALA4880026 | B | GPCRScan assay: inhibition of 5-HT1E | Homo sapiens | 181 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 15. | ALA4880027 | B | GPCRScan assay: inhibition of 5-HT2A | Homo sapiens | 181 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 16. | ALA4880028 | B | GPCRScan assay: inhibition of 5-HT2B | Homo sapiens | 181 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 17. | ALA4880029 | B | GPCRScan assay: inhibition of 5-HT2C | Homo sapiens | 181 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 18. | ALA4880030 | B | GPCRScan assay: inhibition of 5-HT3 | Homo sapiens | 181 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 19. | ALA4880031 | B | GPCRScan assay: inhibition of 5-HT5A | Homo sapiens | 181 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 20. | ALA4880032 | B | GPCRScan assay: inhibition of 5-HT6 | Homo sapiens | 181 | single protein format | Donated Chemical Probes - SGC Frankfurt |
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