# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3787886 | Binding | Inhibition of human recombinant CDK5/p25 using histone H1 as substrate | Homo sapiens | 27 | ALA3784980 | protein complex format | Scientific Literature | |
2. | ALA3787887 | Binding | Inhibition of GST fused human recombinant DYRK1A expressed in Escherichia coli using woodtide as substrate after 30 mins by scintillation counting in presence of [gamma33P]ATP | Homo sapiens | 27 | ALA3784980 | assay format | Scientific Literature | |
3. | ALA3787888 | Binding | Inhibition of pig brain GSK3alpha/GSK3beta using GS-1 as substrate | Sus scrofa | 27 | ALA3784980 | assay format | Scientific Literature | |
4. | ALA3787889 | Binding | Selectivity ratio of IC50 for human recombinant CDK5/p25 to IC50 for pig brain GSK3alpha/GSK3beta | 26 | ALA3784980 | assay format | Scientific Literature | ||
5. | ALA3787890 | Functional | Antiproliferative activity against human HuH7 cells after 48 hrs by Hoechst 3342 staining analysis | Homo sapiens | 28 | ALA3784980 | cell-based format | Scientific Literature | |
6. | ALA3787891 | Functional | Antiproliferative activity against human Caco2 cells after 48 hrs by Hoechst 3342 staining analysis | Homo sapiens | 28 | ALA3784980 | cell-based format | Scientific Literature | |
7. | ALA3787892 | Functional | Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by Hoechst 3342 staining analysis | Homo sapiens | 28 | ALA3784980 | cell-based format | Scientific Literature | |
8. | ALA3787893 | Functional | Antiproliferative activity against human HCT116 cells after 48 hrs by Hoechst 3342 staining analysis | Homo sapiens | 28 | ALA3784980 | cell-based format | Scientific Literature | |
9. | ALA3787894 | Functional | Antiproliferative activity against human PC3 cells after 48 hrs by Hoechst 3342 staining analysis | Homo sapiens | 28 | ALA3784980 | cell-based format | Scientific Literature | |
10. | ALA3787895 | Functional | Antiproliferative activity against human NCI-H727 cells after 48 hrs by Hoechst 3342 staining analysis | Homo sapiens | 28 | ALA3784980 | cell-based format | Scientific Literature | |
11. | ALA2188580 | Functional | Cell cycle arrest in human PC3 cells assessed as accumulation at G1 phase at 1 uM after 24 hrs | Homo sapiens | 1 | ALA2177089 | cell-based format | Scientific Literature | |
12. | ALA2188581 | Functional | Cell cycle arrest in human NCI-H727 cells assessed as accumulation at G1 phase at 1 uM after 24 hrs | Homo sapiens | 1 | ALA2177089 | cell-based format | Scientific Literature | |
13. | ALA2188582 | Functional | Cell cycle arrest in human HCT116 cells assessed as accumulation at G1 phase at 1 uM after 24 hrs | Homo sapiens | 1 | ALA2177089 | cell-based format | Scientific Literature | |
14. | ALA2188583 | Functional | Cell cycle arrest in human Caco2 cells assessed as accumulation at G1 phase at 1 uM after 24 hrs | Homo sapiens | 1 | ALA2177089 | cell-based format | Scientific Literature | |
15. | ALA2188584 | Functional | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at G1 phase at 1 uM after 24 hrs | Homo sapiens | 1 | ALA2177089 | cell-based format | Scientific Literature | |
16. | ALA2188585 | Functional | Cell cycle arrest in human HuH7 cells assessed as accumulation at G1 phase at 1 uM after 24 hrs | Homo sapiens | 1 | ALA2177089 | cell-based format | Scientific Literature | |
17. | ALA2188592 | Functional | Induction of apoptosis in human HCT116 cells assessed as activation of caspase-3 at 1 uM after 24 hrs | Homo sapiens | 1 | ALA2177089 | cell-based format | Scientific Literature | |
18. | ALA2188593 | ADME | Cytotoxicity against human skin fibroblasts cells after 48 hrs | Homo sapiens | 7 | ALA2177089 | cell-based format | Scientific Literature | |
19. | ALA2188988 | Functional | Cytotoxicity against human NCI-H727 cells after 48 hrs | Homo sapiens | 7 | ALA2177089 | cell-based format | Scientific Literature | |
20. | ALA2188989 | Functional | Cytotoxicity against human HCT116 cells after 48 hrs | Homo sapiens | 7 | ALA2177089 | cell-based format | Scientific Literature |