# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3383824 | ADME | Volume of distribution at steady state in dog at 2 mg/kg, iv | Canis lupus familiaris | 2 | ALA3351932 | organism-based format | Scientific Literature | |
2. | ALA3383825 | ADME | Volume of distribution at steady state in monkey at 2 mg/kg, iv | Macaca mulatta | 2 | ALA3351932 | organism-based format | Scientific Literature | |
3. | ALA3383826 | ADME | Clearance in dog at 2 mg/kg, iv | Canis lupus familiaris | 2 | ALA3351932 | organism-based format | Scientific Literature | |
4. | ALA3383827 | ADME | Clearance in monkey at 2 mg/kg, iv | Macaca mulatta | 2 | ALA3351932 | organism-based format | Scientific Literature | |
5. | ALA3383828 | ADME | Half life in dog at 2 mg/kg, iv | Canis lupus familiaris | 2 | ALA3351932 | organism-based format | Scientific Literature | |
6. | ALA3383829 | ADME | Half life in monkey at 2 mg/kg, iv | Macaca mulatta | 2 | ALA3351932 | organism-based format | Scientific Literature | |
7. | ALA3383830 | ADME | Oral bioavailability in dog at 10 mg/kg | Canis lupus familiaris | 2 | ALA3351932 | organism-based format | Scientific Literature | |
8. | ALA3383831 | ADME | Oral bioavailability in monkey at 10 mg/kg | Macaca mulatta | 2 | ALA3351932 | organism-based format | Scientific Literature | |
9. | ALA3383832 | Binding | Inhibition of recombinant Hepatitis C virus genotype 1b Con1 NS5B RNA dependent RNA polymerase delta21 | Hepatitis C virus subtype 1b | 2 | ALA3351932 | assay format | Scientific Literature | |
10. | ALA3383833 | Functional | Antiviral activity against Hepatitis C virus genotype 1a by cell-based replicon assay | Hepacivirus hominis | 2 | ALA3351932 | cell-based format | Scientific Literature | |
11. | ALA3383834 | Functional | Antiviral activity against Hepatitis C virus genotype 1b by cell-based replicon assay | Hepacivirus hominis | 2 | ALA3351932 | cell-based format | Scientific Literature | |
12. | ALA3383835 | ADME | Cytotoxicity against human HuH7 cells assessed as cell viability by MTT assay | Homo sapiens | 2 | ALA3351932 | cell-based format | Scientific Literature | |
13. | ALA3383836 | Functional | Antiviral activity against Hepatitis C virus genotype 1b assessed as shift in EC50 by cell-based replicon assay in presence of 40% human serum | Hepacivirus hominis | 2 | ALA3351932 | cell-based format | Scientific Literature | |
14. | ALA3383837 | ADME | Plasma protein binding in human | Homo sapiens | 2 | ALA3351932 | cell-free format | Scientific Literature | |
15. | ALA3383838 | Physicochemical | Lipophilicity, log D of the compound at pH 7.4 | 2 | ALA3351932 | small-molecule physicochemical format | Scientific Literature | ||
16. | ALA3383839 | ADME | Permeability across apical at pH6 to basolateral side at pH 7.4 in human Caco2 cells | Homo sapiens | 2 | ALA3351932 | cell-based format | Scientific Literature | |
17. | ALA3383840 | ADME | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 2 | ALA3351932 | single protein format | Scientific Literature | |
18. | ALA3383841 | ADME | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 2 | ALA3351932 | single protein format | Scientific Literature | |
19. | ALA3383842 | ADME | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 2 | ALA3351932 | single protein format | Scientific Literature | |
20. | ALA3383843 | ADME | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 2 | ALA3351932 | single protein format | Scientific Literature |