#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2188780	F	Antagonist activity at mineralocorticoid receptor in human Huh7 cells by luciferase reporter gene assay	Homo sapiens	1		cell-based format	Scientific Literature
2.	ALA3301363	P	ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5		4,197		small-molecule physicochemical format	AstraZeneca Deposited Data
3.	ALA3301365	A	ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with whole human plasma at 37C for >5hrs. Method described in B. Testa et al (Eds.), Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies, Wiley-VCH, Weinheim, 2006, pp.119-141. Experimental range 10% to 99.95% bound.	Homo sapiens	1,614		cell-free format	AstraZeneca Deposited Data
4.	ALA3301366	A	ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with whole rat plasma at 37C for >5hrs. Method described in B. Testa et al (Eds.), Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies, Wiley-VCH, Weinheim, 2006, pp.119-141. Experimental range 10% to 99.95% bound.	Rattus norvegicus	717		cell-free format	AstraZeneca Deposited Data
5.	ALA3301370	A	ASTRAZENECA: Intrinsic clearance measured in human liver microsomes following incubation at 37C. Experimental range <3 to >150 microL/min/mg. Rapid Commun. Mass Spectrom. 2010, 24, 1730-1736.	Homo sapiens	1,102		microsome format	AstraZeneca Deposited Data
6.	ALA3301371	A	ASTRAZENECA: Intrinsic clearance measured in rat hepatocytes following incubation at 37C. Experimental range <3 to >150 microL/min/1E6 cells. Rapid Commun. Mass Spectrom. 2010, 24, 1730-1736	Rattus norvegicus	837		cell-based format	AstraZeneca Deposited Data
7.	ALA4008037	B	Antagonist activity at Gal4-fused MR LBD (unknown origin) expressed in human Huh7 cells assessed as inhibition of aldosterone-induced transcriptional activity after 3 hrs by luciferase reporter gene assay	Homo sapiens	7		cell-based format	Scientific Literature
8.	ALA4028141	B	Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation counting	Homo sapiens	15		single protein format	Scientific Literature
9.	ALA4028142	A	Fraction unbound in human liver microsomes	Homo sapiens	1		assay format	Scientific Literature
10.	ALA4028143	A	AUC in Wistar rat at 30 mg/kg, po administered as single dose measured up to 8 hrs post dose by LC-MS analysis	Rattus norvegicus	1		organism-based format	Scientific Literature
11.	ALA4028144	A	AUC in Wistar rat at 500 mg/kg, po administered as single dose measured up to 8 hrs post dose by LC-MS analysis	Rattus norvegicus	1		organism-based format	Scientific Literature
12.	ALA4028145	B	Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction in aldosterone-induced luciferase activity after 16 hrs in presence of serum by luciferase reporter gene assay	Homo sapiens	15		cell-based format	Scientific Literature
13.	ALA4028146	A	Antagonist activity at PR (unknown origin) by Gal4-based cellular assay	Homo sapiens	2		single protein format	Scientific Literature
14.	ALA4028147	A	AUC in Wistar rat at 100 mg/kg, po administered as single dose measured up to 8 hrs post dose by LC-MS analysis	Rattus norvegicus	1		organism-based format	Scientific Literature
15.	ALA4028148	B	Antagonist activity at GR (unknown origin) by Gal4-based cellular assay	Homo sapiens	2		single protein format	Scientific Literature
16.	ALA4028149	A	Antagonist activity at human GAL4-DBD fused AR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction in dihydrotestosterone-induced luciferase activity after 16 hrs by luciferase reporter gene assay	Homo sapiens	2		cell-based format	Scientific Literature
17.	ALA4028150	A	Intrinsic clearance in human liver microsomes	Homo sapiens	15		assay format	Scientific Literature
18.	ALA4028152	A	Intrinsic clearance in rat liver microsomes	Rattus norvegicus	6		assay format	Scientific Literature
19.	ALA4028153	A	Inhibition of CYP1A2 (unknown origin) at 3 uM	Homo sapiens	2		single protein format	Scientific Literature
20.	ALA4028154	A	Inhibition of CYP2D6 (unknown origin) at 3 uM	Homo sapiens	2		single protein format	Scientific Literature