| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2209160 | F | Antiproliferative activity against human MCF7 cells assessed as incorporation of [methyl-3H]thymidine into cellular DNA in serum free medium in in presence of 6.2 ug/mL RNase 1 | Homo sapiens | 2 | ALA2203247 | cell-based format | Scientific Literature | |
| 2. | ALA2209161 | A | Prodrug stability assessed as 4-hydroxytamoxifen release at 40 uM in serum free medium in absence of RNase 1 | 1 | ALA2203247 | assay format | Scientific Literature | ||
| 3. | ALA2209162 | F | Antiproliferative activity against human MCF7 cells assessed as incorporation of [methyl-3H]thymidine into cellular DNA in serum free medium in in absence of 6.2 ug/mL RNase 1 | Homo sapiens | 2 | ALA2203247 | cell-based format | Scientific Literature | |
| 4. | ALA2209163 | P | Prodrug stability assessed as 4-hydroxytamoxifen release at 40 uM in pH 7.4 ribonuclease free 0.10 M sodium phosphate buffer containing NaCl and in absence of RNase 1 | 1 | ALA2203247 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA2209164 | P | Prodrug stability assessed as compound degradation at 37 degC after 11 hrs in absence of ribonuclease 1 at pH 6.0 by HPLC analysis | 1 | ALA2203247 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA2209165 | A | Prodrug activation assessed as half life for ribonuclease 1 mediated 4-hydroxytamoxifen release in MES-NaOH buffer at pH 6.0 by HPLC analysis | 1 | ALA2203247 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!