# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2211966 | B | Binding affinity to human ERG | Homo sapiens | 6 | single protein format | Scientific Literature | ||
2. | ALA2211968 | A | Protein binding in rat plasma | Rattus norvegicus | 11 | cell-free format | Scientific Literature | ||
3. | ALA2211969 | A | Protein binding in human plasma | Homo sapiens | 11 | cell-free format | Scientific Literature | ||
4. | ALA2211970 | A | Efflux ratio assessed as rat MDR1a-mediated directional transport ratio from basolateral to apical over apical to basolateral by cell based assay | Rattus norvegicus | 12 | cell-based format | Scientific Literature | ||
5. | ALA2211971 | A | Efflux ratio assessed as human MDR1-mediated directional transport ratio from basolateral to apical over apical to basolateral by cell based assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
6. | ALA2211972 | A | Passive permeability across MDCK cells | Canis lupus familiaris | 12 | cell-based format | Scientific Literature | ||
7. | ALA2212431 | F | Activity at muscarinic M4 receptor expressing in CHONFAT cells assessed as potentiation of acetylcholine-induced calcium mobilization preincubated for 4 mins and measured 4 mins after acetylcholine stimulation by FLIPR assay | 33 | cell-based format | Scientific Literature | |||
8. | ALA2212432 | F | Activity at muscarinic M3 receptor expressing in CHONFAT cells assessed as potentiation of acetylcholine-induced calcium mobilization preincubated for 4 mins and measured 4 mins after acetylcholine stimulation by FLIPR assay | 33 | cell-based format | Scientific Literature | |||
9. | ALA2212433 | F | Activity at muscarinic M2 receptor expressing in CHONFAT cells assessed as potentiation of acetylcholine-induced calcium mobilization preincubated for 4 mins and measured 4 mins after acetylcholine stimulation by FLIPR assay | 33 | cell-based format | Scientific Literature | |||
10. | ALA2212434 | F | Positive allosteric modulation of human muscarinic M1 receptor expressing in CHONFAT cells assessed as potentiation of acetylcholine-induced calcium mobilization preincubated for 4 mins and measured 4 mins after acetylcholine stimulation by FLIPR assay | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
11. | ALA3128933 | A | Activity at rat MDR1a assessed as ratio of permeability from apical to basolateral side over permeability from basolateral to apical side by cell based assay | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
12. | ALA3128934 | A | Activity at human MDR1 assessed as ratio of permeability from apical to basolateral side over permeability from basolateral to apical side by cell based assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
13. | ALA3128935 | P | Apparent permeability of the compound | 7 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA3362883 | B | Positive allosteric modulation of human mAChR1 expressed in CHONFAT cells assessed as potention of acetylcholine-induced effect incubated for 4 mins prior to acetylcholine addition measured after 4 mins by FLIPR assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
15. | ALA3362886 | P | Apparent passive permeability of the compound | 13 | small-molecule physicochemical format | Scientific Literature | |||
16. | ALA3362887 | A | Effect on human MDR1-mediated drug transport assessed as efflux ratio of permeability from basolateral to apical side over apical to basolateral side | Homo sapiens | 13 | single protein format | Scientific Literature | ||
17. | ALA3362888 | A | Effect on rat MDR1a-mediated drug transport assessed as efflux ratio of permeability from basolateral to apical side over apical to basolateral side | Rattus norvegicus | 13 | assay format | Scientific Literature |