# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA714426 | B | Inhibition of [3H]-(R)-QNB binding to muscarinic receptors of rat brain membranes. | Rattus norvegicus | 14 | cell membrane format | Scientific Literature | ||
2. | ALA747408 | B | In vitro inhibition of [3H]OXO-M binding to Muscarinic receptor from rat cortical homogenates | Rattus norvegicus | 15 | assay format | Scientific Literature | ||
3. | ALA747409 | B | In vitro inhibition of [3H]QNB binding to Muscarinic receptor from rat cortical homogenates | Rattus norvegicus | 15 | assay format | Scientific Literature | ||
4. | ALA746376 | B | The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Value ranges from 6-29 | 1 | tissue-based format | Scientific Literature | |||
5. | ALA743858 | B | The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cortex; Value ranges from 1700-2000 | 1 | tissue-based format | Scientific Literature | |||
6. | ALA749929 | B | Ability to displace radioligand [3H]N-methylscopolamine (NMS) at muscarinic acetylcholine receptor from rat cortical homogenate. | 38 | assay format | Scientific Literature | |||
7. | ALA749931 | B | Affinity to displace radioligand [3H]oxotremorine (OXO) at muscarinic acetylcholine receptor from rat cortical homogenate. | 39 | assay format | Scientific Literature | |||
8. | ALA749940 | B | In vitro for its ability to displace [3H]NMS from muscarinic acetylcholine receptor in rat cortical homogenates | 31 | assay format | Scientific Literature | |||
9. | ALA751545 | B | In vitro binding affinity against muscarinic acetylcholine receptor from rat cortical homogenates using [3H]N-methylscopolamine as radioligand | 31 | assay format | Scientific Literature | |||
10. | ALA751546 | B | In vitro binding affinity against muscarinic acetylcholine receptor from rat cortical homogenates using [3H]oxotremorine-M radioligand | 31 | assay format | Scientific Literature | |||
11. | ALA751547 | B | In vitro binding affinity against cortical muscarinic acetylcholine receptor measured by displacement of [3H]NMS. | 57 | protein format | Scientific Literature | |||
12. | ALA751548 | B | In vitro binding affinity against cortical muscarinic acetylcholine receptor measured by displacement of [3H]OXO-M. | 57 | protein format | Scientific Literature | |||
13. | ALA749814 | B | Relative binding of QNB and OXO-M to muscarininc receptors (ratio of IC50) | Rattus norvegicus | 12 | protein format | Scientific Literature | ||
14. | ALA746865 | B | Ratio of geometric mean of the affinity constant (Kapp) of NMS/OXO-M | 57 | protein format | Scientific Literature | |||
15. | ALA746866 | B | The selectivity ratio of Kapp of NMS/OXO -M | 27 | protein format | Scientific Literature | |||
16. | ALA746354 | B | Compound was tested in vitro for its ability to displace [3H]OXO-M from Muscarinic acetylcholine receptor in rat cortical homogenates | 1 | assay format | Scientific Literature | |||
17. | ALA745462 | B | Ratio of [3H]N-methylscopolamine (NMS) to [3H]oxotremorine (OXO) at muscarinic acetylcholine receptor from rat cortical homogenate. | 37 | assay format | Scientific Literature | |||
18. | ALA795511 | F | Ability to stimulate phosphoinositol metabolism was examined in the rat cerebral cortex at 100 uM | Rattus norvegicus | 14 | organism-based format | Scientific Literature | ||
19. | ALA871722 | B | Log of the ratio of Kapp([3H]-NMS)/Kapp([3H]-OXO-M) was determined | 9 | assay format | Scientific Literature | |||
20. | ALA849918 | B | Ratio of inhibition of QNB to OXO-M binding to Muscarinic receptor | Rattus norvegicus | 15 | protein format | Scientific Literature |