# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA714426 | Binding | Inhibition of [3H]-(R)-QNB binding to muscarinic receptors of rat brain membranes. | Rattus norvegicus | 14 | ALA1126628 | cell membrane format | Scientific Literature | |
2. | ALA795511 | Functional | Ability to stimulate phosphoinositol metabolism was examined in the rat cerebral cortex at 100 uM | Rattus norvegicus | 14 | ALA1126628 | organism-based format | Scientific Literature | |
3. | ALA852858 | Binding | The ratio of Kapp([3H]-NMS) / Kapp([3H]-OXO-M) was determined | 31 | ALA1124736 | protein format | Scientific Literature | ||
4. | ALA849918 | Binding | Ratio of inhibition of QNB to OXO-M binding to Muscarinic receptor | Rattus norvegicus | 15 | ALA1125425 | protein format | Scientific Literature | |
5. | ALA871722 | Binding | Log of the ratio of Kapp([3H]-NMS)/Kapp([3H]-OXO-M) was determined | 9 | ALA1124736 | assay format | Scientific Literature | ||
6. | ALA747408 | Binding | In vitro inhibition of [3H]OXO-M binding to Muscarinic receptor from rat cortical homogenates | Rattus norvegicus | 15 | ALA1125425 | assay format | Scientific Literature | |
7. | ALA747409 | Binding | In vitro inhibition of [3H]QNB binding to Muscarinic receptor from rat cortical homogenates | Rattus norvegicus | 15 | ALA1125425 | assay format | Scientific Literature | |
8. | ALA746376 | Binding | The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]oxotremorine-M from rat cerebral cortex; Value ranges from 6-29 | 1 | ALA1125199 | tissue-based format | Scientific Literature | ||
9. | ALA743858 | Binding | The compound was tested in vitro for central muscarinic acetylcholine receptor affinity to displace [3H]quinuclidinyl benzilate from rat cerebral cortex; Value ranges from 1700-2000 | 1 | ALA1125199 | tissue-based format | Scientific Literature | ||
10. | ALA749929 | Binding | Ability to displace radioligand [3H]N-methylscopolamine (NMS) at muscarinic acetylcholine receptor from rat cortical homogenate. | 38 | ALA1124855 | assay format | Scientific Literature | ||
11. | ALA749931 | Binding | Affinity to displace radioligand [3H]oxotremorine (OXO) at muscarinic acetylcholine receptor from rat cortical homogenate. | 39 | ALA1124855 | assay format | Scientific Literature | ||
12. | ALA749940 | Binding | In vitro for its ability to displace [3H]NMS from muscarinic acetylcholine receptor in rat cortical homogenates | 31 | ALA1124736 | assay format | Scientific Literature | ||
13. | ALA751545 | Binding | In vitro binding affinity against muscarinic acetylcholine receptor from rat cortical homogenates using [3H]N-methylscopolamine as radioligand | 31 | ALA1124973 | assay format | Scientific Literature | ||
14. | ALA751546 | Binding | In vitro binding affinity against muscarinic acetylcholine receptor from rat cortical homogenates using [3H]oxotremorine-M radioligand | 31 | ALA1124973 | assay format | Scientific Literature | ||
15. | ALA751547 | Binding | In vitro binding affinity against cortical muscarinic acetylcholine receptor measured by displacement of [3H]NMS. | 57 | ALA1126146 | protein format | Scientific Literature | ||
16. | ALA751548 | Binding | In vitro binding affinity against cortical muscarinic acetylcholine receptor measured by displacement of [3H]OXO-M. | 57 | ALA1126146 | protein format | Scientific Literature | ||
17. | ALA749814 | Binding | Relative binding of QNB and OXO-M to muscarininc receptors (ratio of IC50) | Rattus norvegicus | 12 | ALA1125199 | protein format | Scientific Literature | |
18. | ALA746865 | Binding | Ratio of geometric mean of the affinity constant (Kapp) of NMS/OXO-M | 57 | ALA1126146 | protein format | Scientific Literature | ||
19. | ALA746866 | Binding | The selectivity ratio of Kapp of NMS/OXO -M | 27 | ALA1124973 | protein format | Scientific Literature | ||
20. | ALA746354 | Binding | Compound was tested in vitro for its ability to displace [3H]OXO-M from Muscarinic acetylcholine receptor in rat cortical homogenates | 1 | ALA1124736 | assay format | Scientific Literature |