| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2209364 | A | Apparent permeability from basolateral to apical side in MDCK2 cells expressing MDR1 in presence of 10 uM verapamil by gamma counting | Canis lupus familiaris | 1 | ALA2203285 | cell-based format | Scientific Literature | |
| 2. | ALA2209365 | A | Apparent permeability from apical to basolateral side in MDCK2 cells expressing MDR1 in presence of 10 uM verapamil by gamma counting | Canis lupus familiaris | 1 | ALA2203285 | cell-based format | Scientific Literature | |
| 3. | ALA2209366 | A | Apparent permeability from basolateral to apical side in MDCK2 cells expressing MDR1 in presence of 100 uM verapamil by gamma counting | Canis lupus familiaris | 1 | ALA2203285 | cell-based format | Scientific Literature | |
| 4. | ALA2209367 | A | Apparent permeability from apical to basolateral side in MDCK2 cells expressing MDR1 in presence of 100 uM verapamil by gamma counting | Canis lupus familiaris | 1 | ALA2203285 | cell-based format | Scientific Literature | |
| 5. | ALA2209368 | A | Permeability from basolateral to apical side in MDCK2 cells expressing MDR1 in presence of 10 uM Pgp inhibitor elacridar by gamma counting | Canis lupus familiaris | 1 | ALA2203285 | cell-based format | Scientific Literature | |
| 6. | ALA2209369 | A | Permeability from apical to basolateral side in MDCK2 cells expressing MDR1 in presence of 10 uM Pgp inhibitor elacridar by gamma counting | Canis lupus familiaris | 1 | ALA2203285 | cell-based format | Scientific Literature | |
| 7. | ALA2209370 | A | Permeability from basolateral to apical side in MDCK2 cells by gamma counting | Canis lupus familiaris | 1 | ALA2203285 | cell-based format | Scientific Literature | |
| 8. | ALA2209371 | A | Permeability from apical to basolateral side in MDCK2 cells by gamma counting | Canis lupus familiaris | 1 | ALA2203285 | cell-based format | Scientific Literature | |
| 9. | ALA2209374 | B | Binding affinity to rat brain histamine H3 receptor after 1 hr by gamma counting | Rattus norvegicus | 1 | ALA2203285 | assay format | Scientific Literature | |
| 10. | ALA2209375 | B | Binding affinity to rat brain histamine H3 receptor assessed as per mg of protein after 1 hr by gamma counting relative to control | Rattus norvegicus | 1 | ALA2203285 | assay format | Scientific Literature | |
| 11. | ALA2209376 | B | Binding affinity to rat histamine H3 receptor low affinity site after 1 hr by Schard plot analysis | Rattus norvegicus | 1 | ALA2203285 | single protein format | Scientific Literature | |
| 12. | ALA2209377 | B | Binding affinity to rat histamine H3 receptor low affinity site assessed as per mg of protein after 1 hr by Schard plot analysis relative to control | Rattus norvegicus | 1 | ALA2203285 | single protein format | Scientific Literature | |
| 13. | ALA2209378 | B | Ratio of Bmax to Kd for rat brain histamine H3 receptor low affinity site relative to rat brain histamine H3 receptor high affinity site | Rattus norvegicus | 1 | ALA2203285 | assay format | Scientific Literature | |
| 14. | ALA2209380 | P | Distribution coefficient, log D of the compound in octanol and PBS buffer at pH 7.4 by shake-flask method | 1 | ALA2203285 | small-molecule physicochemical format | Scientific Literature | ||
| 15. | ALA2209381 | A | Metabolic stability human plasma assessed as parent compound level at 60 MBq after 90 mins by UPLC analysis | Homo sapiens | 1 | ALA2203285 | cell-free format | Scientific Literature | |
| 16. | ALA2209382 | A | Metabolic stability human plasma assessed as compound degradation at 60 MBq after 120 mins by UPLC analysis | Homo sapiens | 1 | ALA2203285 | cell-free format | Scientific Literature | |
| 17. | ALA2209383 | A | Metabolic stability human plasma at 60 MBq after 60 mins by UPLC analysis | Homo sapiens | 1 | ALA2203285 | cell-free format | Scientific Literature | |
| 18. | ALA2209384 | A | Metabolic stability human liver microsome after 120 mins by UPLC analysis | Homo sapiens | 1 | ALA2203285 | microsome format | Scientific Literature | |
| 19. | ALA2209791 | A | Metabolic stability rat liver microsome after 120 mins by UPLC analysis | Rattus norvegicus | 1 | ALA2203285 | microsome format | Scientific Literature | |
| 20. | ALA2211664 | A | Drug uptake in Sprague-Dawley rat striatum at 0.01 nM after 45 mins by autoradiography | Rattus norvegicus | 1 | ALA2203285 | tissue-based format | Scientific Literature |
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