# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2214315 | B | Inhibition of Apaf-1-caspase 9-cytochrome c-caspase 3 complex in human HEK293 cytosolic extract using afc-DEVD as substrate preincubated for 30 mins before substrate addition measured after 30 mins by fluorescence assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA2214316 | B | Inhibition of Apaf-1-caspase 9-cytochrome c (horse) complex assessed as inhibition of release of afc from Ac-LEDH-afc preincubated for 60 mins before substrate addition by fluorescence assay | 6 | assay format | Scientific Literature | |||
3. | ALA2395461 | B | Binding affinity to Apaf1 (unknown origin) assessed as inhibition of procaspase-9 activity | Homo sapiens | 4 | single protein format | Scientific Literature | ||
4. | ALA2395462 | B | Inhibition of recombinant caspase-9 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature |