# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2213984 | A | Cytotoxicity against human 293-EBNA cells assessed as effect on luciferase activity at 10 uM after 1 hr by Photinus reniformis luciferase reporter gene assay | Homo sapiens | 2 | ALA2203017 | cell-based format | Scientific Literature | |
2. | ALA2213985 | B | Inhibition of human STAT6 expressed in 293-EBNA cells assessed as inhibition of IL4-induced STAT6 transcriptional activation at 10 uM after 1 hr by Renilla reniformis luciferase reporter gene assay | Homo sapiens | 2 | ALA2203017 | cell-based format | Scientific Literature | |
3. | ALA2213986 | A | Cytotoxicity against human 293-EBNA cells assessed as effect on luciferase activity at 10 uM after 1 hr by Renilla reniformis luciferase reporter gene assay | Homo sapiens | 2 | ALA2203017 | cell-based format | Scientific Literature | |
4. | ALA2213987 | B | Inhibition of human N-terminal HA/myc tagged STAT6 expressed in 293-EBNA cells assessed as inhibition of IL-4-induced STAT6 inactive dimer-tyrosine phosphorylation after 1 hr by immunoblot analysis | Homo sapiens | 3 | ALA2203017 | cell-based format | Scientific Literature | |
5. | ALA2213988 | B | Inhibition of human STAT6 expressed in 293-EBNA cells assessed as inhibition of IL4-induced STAT6 transcriptional activation at 10 uM after 1 hr by Photinus pylaris luciferase reporter gene assay | Homo sapiens | 2 | ALA2203017 | cell-based format | Scientific Literature | |
6. | ALA2213989 | B | Inhibition of human N-terminal HA/myc tagged STAT6 expressed in 293-EBNA cells assessed as effect on STAT6 dimer configuration after 1 hr by immunoblot analysis | Homo sapiens | 3 | ALA2203017 | cell-based format | Scientific Literature | |
7. | ALA2214425 | B | Binding affinity at human recombinant STAT6 by SPR analysis | Homo sapiens | 3 | ALA2203017 | single protein format | Scientific Literature | |
8. | ALA2214427 | B | Inhibition of JAK2 up to 10 uM after 30 mins by colorimetric ELISA | 2 | ALA2203017 | single protein format | Scientific Literature | ||
9. | ALA2214428 | B | Inhibition of IL-4-induced human STAT6 tyrosine phosphorylation expressed in 293-EBNA cells at 10 uM incubated for 1 hr prior to IL-4-induction measured after 6 hrs by Western blot analysis | Homo sapiens | 3 | ALA2203017 | cell-based format | Scientific Literature | |
10. | ALA2216400 | B | Inhibition of interaction of human recombinant STAT6 with tyrosine phosphorylated IL-4Ralpha peptide at 20 uM after 1 hr by ELISA | Homo sapiens | 3 | ALA2203017 | single protein format | Scientific Literature | |
11. | ALA2216403 | B | Inhibition of mouse STAT6 expressed in BEAS2B cells assessed as IL4-induced eotaxin-3 secretion at 10 uM after 24 hrs by ELISA | Mus musculus | 3 | ALA2203017 | cell-based format | Scientific Literature | |
12. | ALA2216406 | B | Inhibition of mouse STAT6 expressed in BEAS2B cells assessed as inhibition of IL4-induced STAT6 transcriptional activation | Mus musculus | 2 | ALA2203017 | cell-based format | Scientific Literature | |
13. | ALA2209265 | B | Inhibition of human STAT6 expressed in 293-EBNA cells assessed as inhibition of IL4-induced STAT6 transcriptional activation after 1 hr by Photinus pylaris luciferase reporter gene assay | Homo sapiens | 2 | ALA2203017 | cell-based format | Scientific Literature |